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Gene · 51053

GMNN: geminin DNA replication inhibitor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GMNN: geminin DNA replication inhibitor. Genes, record 51053. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51053

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Gene

Symbol
GMNN
HGNC
Name
geminin DNA replication inhibitor
HGNC
NCBI Gene ID
51053
NCBI Gene
HGNC ID
HGNC:17493
HGNC
Ensembl
ENSG00000112312
NCBI Gene
Aliases
Gem, MGORS6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O75496Geminin2096Ensembl, GeneID, HGNC

Source UniProt

Patents69

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19758O75496Espacenet
EP 4641202 A22025-10-294376O75496Espacenet
JP 2025517970 A2025-06-12758O75496Espacenet
JP 2025038035 A2025-03-184369O75496Espacenet
KR 1020250017231 A2025-02-044376O75496Espacenet
US 12134655 B22024-11-054369O75496Espacenet
US 11564998 B22023-01-314749O75496Espacenet
US 11564998 B22023-01-315903O75496Espacenet
US 11446398 B22022-09-2034376O75496Espacenet
US 11446398 B22022-09-2034377O75496Espacenet

1 to 10 of 69

See all 69 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,418

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGMNN papersNewest fiscal year
P30CA016086Cancer Center Support Grant132025
P30CA016672Cancer Center Support Grant112025
P30CA008748Cancer Center Support Grant102025
R35GM127026Cell Signaling and Cell Decisions82025
P30ES010126UNC Center for Environmental Health and Susceptibility72025
P30CA016056Roswell Park Cancer Center Support Grant52025
P30CA023108Cancer Center Support Grant52025
P50CA168504Dana Farber/Harvard Cancer Center Specialized Program of Research Excellence in Breast Cancer52025
ZIABC010411Initiation of DNA Replication in Mammalian Cells52025
P30CA006516Dana-Farber/Harvard Cancer Center42025

1 to 10 of 1,418Source NIH's project files

See all 1,418 nih grants

Papers1,767

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Graph neural network-based risk stratification of prostate cancer using gene expression and SHAP interpretability.PLoS One202642709904PubTator, text miningPubMed
Spatial Genetic Mapping of Normal Human Prostate Tissue Identifies Epithelial Compartments Enriched for Prostate Cancer Association.Mol Carcinog202642669189PubTator, text miningPubMed
Inferring feedback regulation from static snapshots of a single signal.Biochem Biophys Rep202642643853PubTator, text miningPubMed
STUDY OF PREDICTIVE VALUE OF RAD51 EXPRESSION FOR THE EFFECTIVENESS OF PLATINUM-BASED THERAPY OF HIGH-GRADE SEROUS OVARIAN CARCINOMA.Exp Oncol202642634844PubTator, text miningPubMed
Endocrine Phenotypes and Hormonal Treatment in Meier-Gorlin Syndrome: Report of Two Cases and a Systematic Review of Literature.Clin Endocrinol (Oxf)202642496035PubTator, text miningPubMed
Genome-wide association studies identify genetic determinants of synucleinopathy biomarkers.Res Sq202642466396PubTator, text miningPubMed
A Vascular Invasion-Related Gene Signature Identifies NUP35 as a Driver of Angiogenesis and Poor Prognosis in Pancreatic Ductal Adenocarcinoma.Biomedicines202642351681PubTator, text miningPubMed
Predicting DNA replication-related protein expression at the nucleus level from HE: A deep learning study with same-specimen paired data.Acta Histochem202642035593PubTator, text miningPubMed
Prognostic biomarkers related to PANoptosis in esophageal cancer and their immune microenvironment: multi-omics analysis and therapeutic significance.Front Oncol202641930201PubTator, text miningPubMed
SIX3 as a Regulator of Development and Disease.J Dev Biol202641892811PubTator, text miningPubMed

1 to 10 of 1,767

See all 1,767 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51053

GET https://conductscience.org/api/genes/v1/51053/patents?page=2