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Gene · 51056

LAP3: leucine aminopeptidase 3

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. LAP3: leucine aminopeptidase 3. Genes, record 51056. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/51056

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
LAP3
HGNC
Name
leucine aminopeptidase 3
HGNC
NCBI Gene ID
51056
NCBI Gene
HGNC ID
HGNC:18449
HGNC
Ensembl
ENSG00000002549
NCBI Gene
Aliases
HEL-S-106, LAP, LAPEP, PEPS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P28838Cytosol aminopeptidase5190Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026013259 A22026-01-15590P28838Espacenet
EP 4650780 A22025-11-19661P28838Espacenet
JP 2025517970 A2025-06-12661P28838Espacenet
EP 4484957 A12025-01-01208P28838Espacenet
US 11884978 B22024-01-30568P28838Espacenet
WO 2023162878 A2023-08-31208P28838Espacenet
US 11564998 B22023-01-314737P28838Espacenet
US 11446398 B22022-09-2045424P28838Espacenet
US 11446398 B22022-09-2045428P28838Espacenet
JP 2022524081 A2022-04-27148395P28838Espacenet

1 to 10 of 32

See all 32 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
TOSEDOSTATCHEMBL2103847Aminopeptidase inhibitorINHIBITOR

Source ChEMBL

Trials9

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02452346TOSEDOSTATPHASE22018-06-12ClinicalTrials.gov
NCT02352831TOSEDOSTATPHASE1/PHASE22018-12-17ClinicalTrials.gov
NCT01636609TOSEDOSTATPHASE1ClinicalTrials.gov
NCT01567059TOSEDOSTATPHASE2ClinicalTrials.gov
NCT01180426TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00780598TOSEDOSTATPHASE2ClinicalTrials.gov
NCT00737555TOSEDOSTATPHASE1ClinicalTrials.gov
NCT00689000TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov
NCT00522938TOSEDOSTATPHASE1/PHASE2ClinicalTrials.gov

NIH grants681

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant22025
P30CA010815Consolidated Basic Cancer Research Program22025
P30CA012197Cancer Center Support Grant22025
P30CA043703Case Comprehensive Cancer Center Support Grant22025
P30CA068485Cancer Center Support Grant22025
P30DK048520Colorado Nutrition Obesity Research Center22025
R01DK063158Role of Transglutaminase 2 in Celiac Sprue22025
ZIALM594244Evolutionary Analysis and Comparative Genomics of Protein Superfamilies22025
K12GM081266The UCSF IRACDA Scholars Program.12025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens12025

1 to 10 of 681Source NIH's project files

See all 681 nih grants

Papers4,114

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42539046PubTator, text miningPubMed
42105463PubTator, text miningPubMed
42087990PubTator, text miningPubMed
42051728PubTator, text miningPubMed
41974650PubTator, text miningPubMed
41893543PubTator, text miningPubMed
41892316PubTator, text miningPubMed
41881453PubTator, text miningPubMed
41841524PubTator, text miningPubMed
41836418PubTator, text miningPubMed

1 to 10 of 4,114

See all 4,114 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51056

GET https://conductscience.org/api/genes/v1/51056/patents?page=2