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Gene · 51062

ATL1: atlastin GTPase 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATL1: atlastin GTPase 1. Genes, record 51062. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51062

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Gene

Symbol
ATL1
HGNC
Name
atlastin GTPase 1
HGNC
NCBI Gene ID
51062
NCBI Gene
HGNC ID
HGNC:11231
HGNC
Ensembl
ENSG00000198513
NCBI Gene
Aliases
AD-FSP, ATL-1, FSP1, HSN1D, SPG3, SPG3A, atlastin1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8WXF7Atlastin-155814Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1438086Q8WXF7Espacenet
EP 4641201 A22025-10-297547Q8WXF7Espacenet
JP 2025529142 A2025-09-04481Q8WXF7Espacenet
US 12371689 B22025-07-29481Q8WXF7Espacenet
JP 2025517969 A2025-06-127547Q8WXF7Espacenet
JP 2025062604 A2025-04-146963Q8WXF7Espacenet
US 11446398 B22022-09-206963Q8WXF7Espacenet
US 11400116 B22022-08-024134Q8WXF7Espacenet
JP 2022524081 A2022-04-27109934Q8WXF7Espacenet
WO 2020043864 A12020-03-05261Q8WXF7Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,081

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATL1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant92025
P30CA016672Cancer Center Support Grant82025
R01GM107285Mechanism and Role of Membrane Fusion by the Atlastin GTPase72025
R01NS072248Genome Studies in Hereditary Spastic Paraplegia- Beyond the Exome72025
R01GM122923Characterizing the Regulation of Ferroptosis62025
P01CA092584Structural Cell Biology of DNA Repair Machines52025
P30CA068485Cancer Center Support Grant52025
P40OD010440Caenorhabditis Genetics Center52025
K08NS123552Development of a Translational Research Platform to Understand and treat Defective Protein Trafficking in Childhood-Onset Hereditary Spastic Paraplegia42025
P30CA086862Cancer Center Support Grant42025

1 to 10 of 1,081Source NIH's project files

See all 1,081 nih grants

Papers2,411

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Tumor-derived acetylcholine promotes immune evasion in hepatocellular carcinoma by protecting regulatory T cells from ferroptosis.Int Immunopharmacol202642822277PubTator, text miningPubMed
Neutrophil-Driven Inflammation in Pediatric Chronic Recurrent Multifocal Osteomyelitis.Arthritis Rheumatol202642806909PubTator, text miningPubMed
Spatial Association Between Polyamine Metabolism and Lipid Peroxidation in Different Pathological Regions of Glioblastoma.Biomedicines202642792811PubTator, text miningPubMed
Targeting SQLE-Mediated Cholesterol Metabolism to Promote Oxidative Stress and Attenuate Drug Resistance in Osteosarcoma.Antioxidants (Basel)202642792161PubTator, text miningPubMed
Pharmacological targeting of ferroptosis in cancer: mechanisms, tumor immunity, and translational challenges.Pharmacol Rep202642789241PubTator, text miningPubMed
Serum levels of immunoglobulins, tumour markers, and chemokines in gastric cancer patients treated with SOX regimen versus oxaliplatin monotherapy.J Med Biochem202642780944PubTator, text miningPubMed
Ferroptosis in Neurodegenerative Diseases: Iron Dysregulation, GPX4/FSP1 Signaling, and Emerging Neuroprotective Strategies.Curr Neurovasc Res202642770359PubTator, text miningPubMed
Programmed cell death evasion in BRAF V600E-driven primary CNS tumors and thyroid cancer brain metastases.Front Neurol202642769885PubTator, text miningPubMed
Decreased FSP1 expression under chronic hypoxia sensitizes human macrophages towards ferroptosis.Redox Biol202642759111PubTator, text miningPubMed
RNA m6A modification-regulated ferroptosis in cancer: mechanism and therapeutic potential.Front Cell Dev Biol202642755876PubTator, text miningPubMed

1 to 10 of 2,411

See all 2,411 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51062

GET https://conductscience.org/api/genes/v1/51062/patents?page=2