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Gene · 51085

MLXIPL: MLX interacting protein like

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MLXIPL: MLX interacting protein like. Genes, record 51085. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51085

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Gene

Symbol
MLXIPL
HGNC
Name
MLX interacting protein like
HGNC
NCBI Gene ID
51085
NCBI Gene
HGNC ID
HGNC:12744
HGNC
Ensembl
ENSG00000009950
NCBI Gene
Aliases
CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH, bHLHd14
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NP71Carbohydrate-responsive element-binding protein8527Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454023Q9NP71Espacenet
EP 4641201 A22025-10-294932Q9NP71Espacenet
JP 2025147176 A2025-10-068755Q9NP71Espacenet
JP 2025147176 A2025-10-0615305Q9NP71Espacenet
JP 2025529142 A2025-09-047040Q9NP71Espacenet
US 12371689 B22025-07-297040Q9NP71Espacenet
JP 2025517969 A2025-06-124932Q9NP71Espacenet
JP 2025028160 A2025-02-288755Q9NP71Espacenet
JP 2025028160 A2025-02-2815305Q9NP71Espacenet
KR 1020250010750 A2025-01-218755Q9NP71Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,796

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMLXIPL papersNewest fiscal year
P30DK020541NYR-Diabetes Research Center (NYR-DRC)162025
P30DK020572Michigan Diabetes Research Center (MDRC)102025
P30DK063491Diabetes Research Center (DRC)102025
P30DK036836Diabetes Research Center72025
P30CA042014Cancer Center Support Grant62025
P30DK079626UAB Diabetes Research Center62025
P30ES010126UNC Center for Environmental Health and Susceptibility62025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal62025
UL1TR001863Yale Clinical and Translational Science Award62025
ZIAHG000024Genetic analysis of type II diabetes62025

1 to 10 of 1,796Source NIH's project files

See all 1,796 nih grants

Papers2,455

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
FGF21 elevation is a biomarker of citrin deficiency and its metabolic dysregulation in pediatric patients.Mol Genet Metab202642771915PubTator, text miningPubMed
Indole-benzimidazole hybrids modulate lipid metabolism and promote autophagic and apoptotic signaling in breast cancer.Naunyn Schmiedebergs Arch Pharmacol202642722901PubTator, text miningPubMed
Integrative Transcriptomic Analysis and Functional Validation Implicate GPT2 in Glycolytic Regulation in Polycystic Ovary Syndrome.Food Sci Nutr202642707623PubTator, text miningPubMed
Proteomic analysis of pancreatic endocrine cells by mechanistic single-cell isolation identifies membrane pathways.Exp Mol Med202642693238PubTator, text miningPubMed
Sugar Shockwaves: How the Fructose-Glucose-ChREBP Pathway Hijacks Liver Metabolism.Life (Basel)202642653001PubTator, text miningPubMed
BHLHE40 and ChREBP associate with hepatic enhancer clusters containing PPARα, RXRα, and HNF4 nuclear receptors.Endocrinology202642626966PubTator, text miningPubMed
XYLB promotes malignant behaviors of triple-negative breast cancer via SUSD3 upregulation.Mol Cell Biochem202642606683PubTator, text miningPubMed
TRPC6-mediated calcium signaling is involved in T2DM-induced hepatic steatosis and fibrosis and the modulation of ginsenoside Rg1.J Pharmacol Sci202642481130PubTator, text miningPubMed
Hepatic Cholesteryl Ester Transfer Protein Regulates Sex-specific Liver Metabolic Adaptation and Metabolic-Associated Steatotic Liver Disease Risk in Diet-induced Obesity.bioRxiv202642427599PubTator, text miningPubMed
Ketohexokinase: A central mediator of fructose-associated pathogenesis and promising therapeutic target.Pharmacol Res202642379433PubTator, text miningPubMed

1 to 10 of 2,455

See all 2,455 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51085

GET https://conductscience.org/api/genes/v1/51085/patents?page=2