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PCNA: proliferating cell nuclear antigen

1 protein, 163 patents, 0 drugs, 0 trials, 13,295 NIH grants and 39,920 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPCNAHGNC
Nameproliferating cell nuclear antigenHGNC
NCBI Gene ID5111NCBI Gene
HGNC IDHGNC:8729HGNC
EnsemblENSG00000132646NCBI Gene
AliasesATLD2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P12004DNA sliding clamp PCNA261102Ensembl, GeneID, HGNCUniProt

Patents 163

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910121P12004Espacenet
US 12435030 B22025-10-072P12004Espacenet
EP 4616910 A22025-09-172P12004Espacenet
JP 2025128193 A2025-09-022P12004Espacenet
JP 2025517970 A2025-06-1210121P12004Espacenet
WO 2025101862 A12025-05-153P12004Espacenet
WO 2025093618 A12025-05-086P12004Espacenet
JP 2025038035 A2025-03-184428P12004Espacenet
KR 1020250026875 A2025-02-252P12004Espacenet
US 12150938 B22024-11-266P12004Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 13295

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1892,025NIH's project files
P01CA092584Structural Cell Biology of DNA Repair Machines1112,025NIH's project files
P30CA008748Cancer Center Support Grant942,025NIH's project files
P01CA013106Targeting Transcription and Splicing in Cancer582,025NIH's project files
P30CA016086Cancer Center Support Grant562,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)562,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase422,025NIH's project files
P30CA016058Cancer Center Support Grant362,025NIH's project files
P30CA033572Cancer Center Support Grant362,025NIH's project files
P30CA047904Cancer Center Support Grant342,025NIH's project files

Papers 39920

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825327PubTator, text miningPubMed
42818227PubTator, text miningPubMed
42816943PubTator, text miningPubMed
42811975PubTator, text miningPubMed
42811434PubTator, text miningPubMed
42809212PubTator, text miningPubMed
42808670PubTator, text miningPubMed
42806616PubTator, text miningPubMed
42804466PubTator, text miningPubMed
42800802PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license