Gene · 51135
Papers3,419
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
141 to 160 of 3,419
Download this page as JSON| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Interleukin-1 Receptor-Associated Kinase 1 in Cancer Metastasis and Therapeutic Resistance: Mechanistic Insights and Translational Advances. | Cells | 2024 | 39451208 | PubTator, text mining | PubMed |
| Methotrexate promotes the release of granulocyte-macrophage colony-stimulating factor from rheumatoid arthritis fibroblast-like synoviocytes via autocrine interleukin-1 signaling. | Arthritis Res Ther | 2024 | 39394168 | PubTator, text mining | PubMed |
| Discovery of the First Clinical Protein Degrader for the Treatment of Autoimmune Indications: Orally Bioavailable and Selective IRAK4 Degrader KT-474. | J Med Chem | 2024 | 39376047 | PubTator, text mining | PubMed |
| [Novel therapies for MDS and future prospects]. | Rinsho Ketsueki | 2024 | 39358299 | PubTator, text mining | PubMed |
| CXCR1 and CXCR2 are potential neutrophil extracellular trap-related treatment targets in ulcerative colitis: insights from Mendelian randomization, colocalization and transcriptomic analysis. | Front Immunol | 2024 | 39328405 | PubTator, text mining | PubMed |
| Therapeutic compounds targeting interleukin-1 receptor-associated kinase 4 (IRAK4): an updated patent review (2019 to present). | Expert Opin Ther Pat | 2024 | 39327780 | PubTator, text mining | PubMed |
| Severe invasive infections linked to IRAK2 immune variants. | Int J Infect Dis | 2024 | 39299377 | PubTator, text mining | PubMed |
| The immune function of TLR4-1 gene in Octopus sinensis revealed by RNAi and RNA-seq. | Fish Shellfish Immunol | 2024 | 39265964 | PubTator, text mining | PubMed |
| Extrapolating Lessons from Targeted Protein Degradation to Other Proximity-Inducing Drugs. | ACS Chem Biol | 2024 | 39264973 | PubTator, text mining | PubMed |
| Activation of NF-κB/MAPK signaling and induction of apoptosis by salicylate synthase NbtS in Nocardia farcinica promotes neuroinflammation development. | mSystems | 2024 | 39240104 | PubTator, text mining | PubMed |
| Leveraging multiple data types for improved compound-kinase bioactivity prediction. | Nat Commun | 2024 | 39217147 | PubTator, text mining | PubMed |
| Surface-mutagenesis strategies to enable structural biology crystallization platforms. | Acta Crystallogr D Struct Biol | 2024 | 39207897 | PubTator, text mining | PubMed |
| Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases. | J Med Chem | 2024 | 39151120 | PubTator, text mining | PubMed |
| Interleukin-1 receptor-associated kinase 4 (IRAK4) is a critical regulator of inflammatory signalling through toll-like receptors 4 and 7/8 in murine and human lungs. | Br J Pharmacol | 2024 | 39137914 | PubTator, text mining | PubMed |
| α-IRAK-4 Suppresses the Activation of RANK/RANKL Pathway on Macrophages Exposed to Endodontic Microorganisms. | Int J Mol Sci | 2024 | 39126003 | PubTator, text mining | PubMed |
| RNF149 negatively regulates LPS/TLR4 signal transduction by ubiquitination-mediated CD63 degradation. | Heliyon | 2024 | 39104473 | PubTator, text mining | PubMed |
| Endogenously produced itaconate negatively regulates innate-driven cytokine production and drives global ubiquitination in human macrophages. | Cell Rep | 2024 | 39093697 | PubTator, text mining | PubMed |
| Geraniin from the methanol extract of Pilea mongolica suppresses LPS-induced inflammatory responses by inhibiting IRAK4/MAPKs/NF-κB/AP-1 pathway in HaCaT cells. | Int Immunopharmacol | 2024 | 39083922 | PubTator, text mining | PubMed |
| Unconventional posttranslational modification in innate immunity. | Cell Mol Life Sci | 2024 | 38970666 | PubTator, text mining | PubMed |
| Construction of IRAK4 inhibitor activity prediction model based on machine learning. | Mol Divers | 2024 | 38970641 | PubTator, text mining | PubMed |
gene-search-2026-11-11-0.2.0
Sources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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