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Gene · 5116

PCNT: pericentrin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PCNT: pericentrin. Genes, record 5116. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5116

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Gene

Symbol
PCNT
HGNC
Name
pericentrin
HGNC
NCBI Gene ID
5116
NCBI Gene
HGNC ID
HGNC:16068
HGNC
Ensembl
ENSG00000160299
NCBI Gene
Aliases
KEN, KIAA0402, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95613Pericentrin3,3360Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457341O95613Espacenet
EP 4641201 A22025-10-297722O95613Espacenet
JP 2025517969 A2025-06-127722O95613Espacenet
JP 2022141755 A2022-09-29185O95613Espacenet
US 11446398 B22022-09-2061922O95613Espacenet
JP 2022524081 A2022-04-27164893O95613Espacenet
US 11078247 B22021-08-038216O95613Espacenet
JP 2019054813 A2019-04-11237776O95613Espacenet
US 10130590 B22018-11-2038O95613Espacenet
JP 2017121241 A2017-07-13237776O95613Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,882

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePCNT papersNewest fiscal year
P30CA014520UW Comprehensive Cancer Center Support122025
P30CA008748Cancer Center Support Grant92025
P30CA016672Cancer Center Support Grant92025
P30CA021765Cancer Center Support Grant (CCSG)92025
ZIABC011459Control of centrosome biogenesis72025
P30CA016086Cancer Center Support Grant62025
P30CA068485Cancer Center Support Grant62025
P30ES010126UNC Center for Environmental Health and Susceptibility62025
P50CA116201Mayo Clinic Breast Cancer SPORE62025
ZIAHL006126Centrosome Regulation in Development and Dysregulation in Disease62025

1 to 10 of 1,882Source NIH's project files

See all 1,882 nih grants

Papers2,141

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Aberrant PCM1 accumulation in Trisomy 21 mislocalizes E3 ligases, delaying primary ciliogenesis.bioRxiv202642779918PubTator, text miningPubMed
Divergent microtubule-organizing center strategies in mammalian gametogenesis.Trends Open202642761981PubTator, text miningPubMed
Whole-exome Sequencing Identifies Novel Candidate PCNT Variants in a Child With Overlapping MOPD II Features: A Case Report.J Vis Exp202642611633PubTator, text miningPubMed
[Microcephalic osteodysplastic primary dwarfism type II with hypergonadotropic hypogonadism in a 16-year-old patient].Probl Endokrinol (Mosk)202642545326PubTator, text miningPubMed
Human Sperm Centrosome: From Current Evidence to Future Perspectives-A Systematic Review.Life (Basel)202642355448PubTator, text miningPubMed
Activating adaptor-like sequences in pericentrin mediate its transport by dynein.bioRxiv202642244606PubTator, text miningPubMed
A MOPD II-associated Pericentrin variant disrupts PACT domain dimerization and pericentriolar material recruitment.bioRxiv202642146478PubTator, text miningPubMed
Emerin is necessary for microtubule-organizing center translocation to the nuclear envelope of muscle cells.Cell Death Dis202642120880PubTator, text miningPubMed
A human CEP120 gene variant impairs meiotic spindle building causing aneuploidy†.Biol Reprod202642096526PubTator, text miningPubMed
Complex aberrant expression of planar nuclear polarity factors in intraductal papillary mucinous neoplasm of the pancreas.Virchows Arch202641902867PubTator, text miningPubMed

1 to 10 of 2,141

See all 2,141 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5116

GET https://conductscience.org/api/genes/v1/5116/patents?page=2