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Gene · 51185

Papers2,935

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

121 to 140 of 2,935

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TitleJournalYearPMIDFound bySource
Direct-to-Biology: Streamlining the Path From Chemistry to Biology in Drug Discovery.ChemMedChem202641716046PubTator, text miningPubMed
PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington's Disease.J Am Chem Soc202641712780PubTator, text miningPubMed
High-throughput ligand diversification to discover chemical inducers of proximity.Nat Chem Biol202641699285PubTator, text miningPubMed
Discovery of KRAS-G12D degraders via exploration of various E3 ligases.Eur J Med Chem202641679196PubTator, text miningPubMed
Synthesis and biological evaluation of Retro-2-based PROTACs reveal PEG-linker length and warhead impact on GSPT1 degradation.Eur J Med Chem202641672026PubTator, text miningPubMed
Discovery of BMS-986458, a Potent and Selective B-Cell Lymphoma 6 Protein Ligand-Directed Degrader, for the Treatment of B-Cell Non-Hodgkin Lymphoma.J Med Chem202641670385PubTator, text miningPubMed
Targeting Ikaros and Aiolos: Next-Generation Cereblon E3 Ligase Modulators in MM.Eur J Haematol202641651798PubTator, text miningPubMed
Emerging biologic modalities for targeted protein degradation.J Biol Chem202641651431PubTator, text miningPubMed
Targeted degradation of BRD4 by PROTACs: advances in cancer therapy.Chem Commun (Camb)202641635951PubTator, text miningPubMed
HBE-843, a Novel, Potent, and Selective EGFR Targeting PROTAC for the Treatment of Non-Small-Cell Lung Cancer.Arch Pharm (Weinheim)202641635121PubTator, text miningPubMed
Development of PolyHis-Targeting PROTAC Degraders.Angew Chem Int Ed Engl202641630184PubTator, text miningPubMed
Mezigdomide combined with bortezomib disrupts the cell cycle and elicits superior antitumor effects in multiple myeloma.Blood Neoplasia202641626055PubTator, text miningPubMed
From Serendipity to Strategy: Rationalizing Molecular Glue Discovery and Proximity-Induced Pharmacology through Chemical Biology.J Am Chem Soc202641622634PubTator, text miningPubMed
The role of m6A RNA methyltransferase METTL3 in drug resistance mechanisms in acute myeloid leukemia.Blood Res202641615563PubTator, text miningPubMed
Rifamycin O as a novel CRBN ligand for targeted degradation of IKZF1/3 proteins in hematopoietic malignancies.Acta Pharm Sin B202641584346PubTator, text miningPubMed
Understanding the Role of H-Bonds in the Stability of Molecular Glue-Induced Ternary Complexes.J Chem Inf Model202641572929PubTator, text miningPubMed
Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation.Life Sci Alliance202641571434PubTator, text miningPubMed
Identification of an allosteric site on the E3 ligase adapter cereblon.Nature202641565821Swiss-Prot, curatedPubMed
Cereblon induces G3BP2 neosubstrate degradation using molecular surface mimicry.Nat Struct Mol Biol202641559416PubTator, text miningPubMed
Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors.Commun Chem202641554911PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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