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Gene · 51203

NUSAP1: nucleolar and spindle associated protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NUSAP1: nucleolar and spindle associated protein 1. Genes, record 51203. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51203

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Gene

Symbol
NUSAP1
HGNC
Name
nucleolar and spindle associated protein 1
HGNC
NCBI Gene ID
51203
NCBI Gene
HGNC ID
HGNC:18538
HGNC
Ensembl
ENSG00000137804
NCBI Gene
Aliases
ANKT, BM037, FLJ13421, LNP, NUSAP, PRO0310p1, Q0310, SAPL
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BXS6Nucleolar and spindle-associated protein 14410Ensembl, GeneID, HGNC

Source UniProt

Patents13

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456273Q9BXS6Espacenet
EP 4650780 A22025-11-1916916Q9BXS6Espacenet
EP 4641201 A22025-10-2920894Q9BXS6Espacenet
EP 4641202 A22025-10-298488Q9BXS6Espacenet
JP 2025517969 A2025-06-1220894Q9BXS6Espacenet
JP 2025517970 A2025-06-1216916Q9BXS6Espacenet
KR 1020250017231 A2025-02-048488Q9BXS6Espacenet
US 11446398 B22022-09-2058689Q9BXS6Espacenet
JP 2022524081 A2022-04-27161660Q9BXS6Espacenet
JP 2019054813 A2019-04-11236708Q9BXS6Espacenet

1 to 10 of 13

See all 13 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants782

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNUSAP1 papersNewest fiscal year
R01AI157975Novel nanobodies to prevent and treat SARS-CoV-2 and other pathogenic human coronaviruses52025
P30CA016058Cancer Center Support Grant42025
R01HL146736Delivering inhalable nanoparticles containing AI-optimized CFTR mRNA with a novel microfluidic device for treatment of CF42025
P30CA016086Cancer Center Support Grant32025
P30CA016087Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA023108Cancer Center Support Grant32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
P30CA068485Cancer Center Support Grant32025
P51OD011132Emory National Primate Research Center32025

1 to 10 of 782Source NIH's project files

See all 782 nih grants

Papers1,551

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
High Infiltration Level of a Prognostic Improvement Associated T Cells Is Favorable for the Prognosis of Patients with Gastric Adenocarcinoma.Digestion202642771562PubTator, text miningPubMed
Pathogenicity of NUSAP1 Variants Is Defined by NMD-Escape: Evidence From Two Novel Cases and Systematic Population-Based Variant Analysis.Clin Genet202642706591PubTator, text miningPubMed
Nusap-dependent inhibition of Separase in meiosis.Sci China Life Sci202642700219PubTator, text miningPubMed
Targeted mRNA Delivery Using Bispecific Antibody-Lipid Nanoparticle Complexes.Mol Pharm202642473281PubTator, text miningPubMed
Age-dependent electroclinical evolution from focal seizures to epileptic spasms in NUSAP1-related malformations of cortical development.Epileptic Disord202642322211PubTator, text miningPubMed
Hypoxia-induced m6A demethylation promotes hepatocellular carcinoma progression by preventing the degradation of Gal-1 mRNA.Genes Dis202642290655PubTator, text miningPubMed
SPP1+ macrophages facilitate the differentiation and maturation of regulatory T cells in tumour-draining lymph nodes of colorectal cancer.Gut202642285754PubTator, text miningPubMed
Nucleolar and spindle-associated protein 1 (NUSAP1) promotes thyroid cancer dedifferentiation via BCAT1-mediated metabolic-epigenetic crosstalk.Int J Biol Macromol202642276487PubTator, text miningPubMed
mRNA delivery of a class 1/4 SARS-CoV-2 neutralizing antibody protects against diverse sarbecoviruses in a lethal mouse challenge model.Proc Natl Acad Sci U S A202642258728PubTator, text miningPubMed
SLC25A51 mRNA-LNP Armors T Cells with Mitochondrial Fitness in Cancer Treatment.ACS Appl Mater Interfaces202642226663PubTator, text miningPubMed

1 to 10 of 1,551

See all 1,551 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51203

GET https://conductscience.org/api/genes/v1/51203/patents