Gene · 51206
GP6: glycoprotein VI platelet
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GP6: glycoprotein VI platelet. Genes, record 51206. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51206
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9HCN6 | Platelet glycoprotein VI | 339 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48057 | Q9HCN6 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6120 | Q9HCN6 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1758 | Q9HCN6 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6525 | Q9HCN6 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1758 | Q9HCN6 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6525 | Q9HCN6 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 6120 | Q9HCN6 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 6120 | Q9HCN6 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 6127 | Q9HCN6 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 35696 | Q9HCN6 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| GLENZOCIMAB | CHEMBL4650395 | Platelet glycoprotein VI (GPVI) inhibitor | INHIBITOR |
Source ChEMBL
Trials5
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06437431 | GLENZOCIMAB | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT05559398 | GLENZOCIMAB | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT05070260 | GLENZOCIMAB | PHASE2/PHASE3 | ClinicalTrials.gov | |
| NCT04659109 | GLENZOCIMAB | PHASE2 | ClinicalTrials.gov | |
| NCT03803007 | GLENZOCIMAB | PHASE1/PHASE2 | ClinicalTrials.gov |
NIH grants1,402
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GP6 papers | Newest fiscal year |
|---|---|---|---|
| R01HL101972 | Characterization of Coagulation Factor-platelet Interactions: Role of FXI | 28 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P51OD011092 | Support for National Primate Research Center | 8 | 2025 |
| P30CA069533 | OHSU Knight Cancer Institute | 7 | 2025 |
| P30EY010572 | Ophthalmology Core Facility | 5 | 2025 |
| R01HL144113 | Contact Pathway Activation on Vascular Devices | 5 | 2025 |
| ZIAHL006170 | Cardiovascular Genomics and Bioinformatics projects | 5 | 2025 |
| R01HL162940 | Computational Modeling of Device-Induced Platelet Activation and Receptor Shedding Relevant to Thrombosis and Bleeding in Device-Assisted Circulation | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
1 to 10 of 1,402Source NIH's project files
See all 1,402 nih grantsPapers3,850
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Inhibition of mitochondrial permeability transition selectively suppresses thrombogenic platelet procoagulant activity. | Blood | 2026 | 42821743 | PubTator, text mining | PubMed |
| A Boolean Seven-Layer Platelet Decision Model Models Consistently the Logic and Semiquantitatively the Dynamics of Platelet Activation and Inhibition. | Comput Struct Biotechnol J | 2026 | 42819776 | PubTator, text mining | PubMed |
| Circulating Proteins as Predictors of Improvement in Physical Function in Hospitalized Older Adults with Geriatric Syndromes: Findings from the REHAB-HF Trial. | medRxiv | 2026 | 42818424 | PubTator, text mining | PubMed |
| Differential inhibition of bispecific GPVI and CLEC-2 nanobody ligands by a monovalent nanobody. | Thromb Res | 2026 | 42805106 | PubTator, text mining | PubMed |
| Platelet glycoprotein VI in platelet-neutrophil interactions: From complex formation to neutrophil extracellular trap-associated pathology. | Int Immunopharmacol | 2026 | 42763243 | PubTator, text mining | PubMed |
| Study of centrifugal blood pump non-physiological shear stress induced platelet hemostatic dysfunction. | Thromb Res | 2026 | 42743859 | PubTator, text mining | PubMed |
| Platelets mediate fibrin-induced thromboinflammation and NETosis through a GPVI-polyphosphate-FXIIa procoagulant axis. | Blood Vessel Thromb Hemost | 2026 | 42729624 | PubTator, text mining | PubMed |
| Construction of molecular signatures based on the co-expression network of NECSO-related gene TRPM4 and its prognostic value in hepatocellular carcinoma. | J Gastrointest Oncol | 2026 | 42703320 | PubTator, text mining | PubMed |
| Predicting Device-Induced Platelet Damage in Assisted Circulation Using a New Biophysical Model and Experimental Validation. | Artif Organs | 2026 | 42698235 | PubTator, text mining | PubMed |
| Comparative analysis of human papilloma virus detection methods and prognostic significance of transcriptionally active viral load in oropharyngeal squamous cell carcinoma. | Oral Oncol | 2026 | 42696859 | PubTator, text mining | PubMed |
1 to 10 of 3,850
See all 3,850 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/51206
GET https://conductscience.org/api/genes/v1/51206/patents?page=2