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UBR5: ubiquitin protein ligase E3 component n-recognin 5
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Gene · 51366

Papers1,630

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,630

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TitleJournalYearPMIDFound bySource
UBR5-KDM5A axis rewires redox metabolism to confer cisplatin resistance in triple-negative breast cancer via the cAMP-PKA-SIRT3 cascade.Drug Resist Updat202642809895PubTator, text miningPubMed
JNK acts as a molecular brake of the CDC73 positive feedback loop to modulate osteosarcoma malignant progression via UBR5.Oncogene202642749759PubTator, text miningPubMed
Dynamic Prediction of Survival Outcomes in Multiple Myeloma.Cancers (Basel)202642738384PubTator, text miningPubMed
Correction to: UBR-box containing protein, UBR5, is overexpressed in human lung adenocarcinoma and is a potential therapeutic target.BMC Cancer202642717320PubTator, text miningPubMed
UV-B enhances hyperaccumulation of α- and β-carotene in marigold petals.Plant Physiol Biochem202642526340PubTator, text miningPubMed
Mechanistic and functional study of lncRNA SNHG3/miR-128-3p/UBR5 axis in neuroinflammation in Alzheimer's disease.J Gerontol A Biol Sci Med Sci202642502987PubTator, text miningPubMed
Pan-cancer proteogenomic interrogation of the ubiquitin-proteasome system.Cell Death Differ202642472879PubTator, text miningPubMed
Network pharmacology combined with molecular docking to investigate the potential role of curcumin targeting TGR5 to modulate the GLP-1 pathway in T2DM with obesity.Pak J Pharm Sci202642433074PubTator, text miningPubMed
Distinct Proteasomal Pathways Drive Oncogenic PPM1D Activation.bioRxiv202642282570PubTator, text miningPubMed
Defining a Novel 8q22.3 Microdeletion Syndrome Caused by UBR5 Haploinsufficiency.Pediatr Neurol202642263457PubTator, text miningPubMed
lnc122 RNA prevents liver tumorigenesis in MYC-driven liver cancer.JHEP Rep202642250762PubTator, text miningPubMed
SIRT5-dependent desuccinylation licenses UBR5-mediated degradation of TAMM41 to regulate mitochondrial metabolism in lung adenocarcinoma.Biol Direct202642186063PubTator, text miningPubMed
Viperin weakens IFN-I-induced immune activity by facilitating STAT1 degradation through E3 ligase UBE4A.Cell Insight202642058507PubTator, text miningPubMed
Chromatin association promotes UBR5-mediated degradation of Rb.bioRxiv202642039660PubTator, text miningPubMed
Disruption of the SAGA CORE triggers collateral degradation of KAT2A.Nat Commun202642009663PubTator, text miningPubMed
The E3 ubiquitin ligase UBR5 promotes ubiquitylation and degradation of the chromatin regulator ATAD2.FEBS Lett202641978312Swiss-Prot, curatedPubMed
Turnover of missense mutant cytosolic proteins proceeds in the absence of major quality control E3 ligases.MicroPubl Biol202641969808PubTator, text miningPubMed
Toward a transcriptional map of the turkey adenovirus 3 (TAdV-3) genome.Avian Pathol202641960683PubTator, text miningPubMed
E3 Ubiquitin Ligase UBR5 Aggravates Cardiac Hypertrophy Via Inhibiting Nrf2/HO-1 Pathway.Cardiovasc Drugs Ther202641824182PubTator, text miningPubMed
Switching of the c-Myc protein degradation pathway depending on the PP2A-B55α complex levels.Proc Natl Acad Sci U S A202641818150PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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