Gene · 51393
TRPV2: transient receptor potential cation channel subfamily V member 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TRPV2: transient receptor potential cation channel subfamily V member 2. Genes, record 51393. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51393
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y5S1 | Transient receptor potential cation channel subfamily V member 2 | 764 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents57
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 67658 | Q9Y5S1 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6724 | Q9Y5S1 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6490 | Q9Y5S1 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5077 | Q9Y5S1 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5077 | Q9Y5S1 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6490 | Q9Y5S1 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6724 | Q9Y5S1 | Espacenet |
| JP 2023169439 A | 2023-11-30 | 1 | Q9Y5S1 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 90378 | Q9Y5S1 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 4172 | Q9Y5S1 | Espacenet |
1 to 10 of 57
See all 57 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants777
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TRPV2 papers | Newest fiscal year |
|---|---|---|---|
| R01CA206573 | Structure and function of Transient Receptor Potential Channels | 12 | 2025 |
| R01NS107253 | Single-Particle Cryo-EM Characterization of AMPA Receptor Functional States | 10 | 2025 |
| R01AR078814 | Structural and functional principles of activation and regulation of the transient receptor potential channel TRPV3. | 5 | 2025 |
| R01GM093290 | Regulation of the epithelial Ca2+ channels TRPV6 and TRPV5 | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| ZIANS002945 | Gating mechanisms and pharmacology of voltage-activated ion channels | 4 | 2025 |
| P30EY014800 | University of Utah Core Vision Research Grant | 3 | 2025 |
| R01EY027920 | Molecular mechanisms of mechanotransduction in the aqueous outflow pathway | 3 | 2025 |
| R35GM144120 | Structure and Function of TRPV channels | 3 | 2025 |
| T32EY024234 | Vision Research Training Grant at the University of Utah | 3 | 2025 |
1 to 10 of 777Source NIH's project files
See all 777 nih grantsPapers1,706
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Correction to "Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression". | ACS Cent Sci | 2026 | 42799159 | PubTator, text mining | PubMed |
| Characterization of TRPV2-associated pathology in Parkinson's disease and therapeutic modulation using Tranilast. | Front Cell Neurosci | 2026 | 42625634 | PubTator, text mining | PubMed |
| Structural origins of species-specific differences in TRPV2 activation. | Nat Commun | 2026 | 42624855 | PubTator, text mining | PubMed |
| Inactivation Switch for Run-up in TRPV2. | Res Sq | 2026 | 42620408 | PubTator, text mining | PubMed |
| Correction: Novel recombinant protein PK5-Gal-3C enhances the anti-tumor activity of T cells via binding with TRPV2. | Cancer Immunol Immunother | 2026 | 42616099 | PubTator, text mining | PubMed |
| Transient receptor potential vanilloid 2 functions as a directional driver for hepoxilin A3-mediated neutrophil migration. | Sci Adv | 2026 | 42536751 | PubTator, text mining | PubMed |
| Transient receptor potential vanilloid channels in inflammatory bowel diseases: linking inflammation, angiogenesis, and oxidative stress. | Inflammopharmacology | 2026 | 42507268 | PubTator, text mining | PubMed |
| Structural insights and regulatory mechanisms of endogenous modulation of TRPV2 as a potential drug target. | Biochem Pharmacol | 2026 | 42498156 | PubTator, text mining | PubMed |
| Structure-based virtual screening for selective connexin hemichannel blockers: a historical perspective on the discovery of a small organic inhibitor. | Front Pharmacol | 2026 | 42428492 | PubTator, text mining | PubMed |
| Pharmacological modulation of TRPV2 enhances migration and induces Immunoglobulin E (IgE)-independent degranulation of mast cells. | Cell Calcium | 2026 | 42424794 | PubTator, text mining | PubMed |
1 to 10 of 1,706
See all 1,706 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/51393
GET https://conductscience.org/api/genes/v1/51393/patents?page=2