ConductScience.org, home

Gene · 51428

DDX41: DEAD-box helicase 41

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. DDX41: DEAD-box helicase 41. Genes, record 51428. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51428

On this page

Gene

Symbol
DDX41
HGNC
Name
DEAD-box helicase 41
HGNC
NCBI Gene ID
51428
NCBI Gene
HGNC ID
HGNC:18674
HGNC
Ensembl
ENSG00000183258
NCBI Gene
Aliases
ABS, MGC8828, MPLPF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UJV9Probable ATP-dependent RNA helicase DDX416225Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1443315Q9UJV9Espacenet
JP 2024504002 A2024-01-3080Q9UJV9Espacenet
JP 2024502755 A2024-01-2379Q9UJV9Espacenet
JP 2024500874 A2024-01-1080Q9UJV9Espacenet
JP 2024500877 A2024-01-1080Q9UJV9Espacenet
US 11446398 B22022-09-2023000Q9UJV9Espacenet
JP 2022537570 A2022-08-2679Q9UJV9Espacenet
JP 2022524081 A2022-04-27125971Q9UJV9Espacenet
US 11078247 B22021-08-032969Q9UJV9Espacenet
JP 2019054813 A2019-04-11223750Q9UJV9Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,108

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleDDX41 papersNewest fiscal year
P30CA008748Cancer Center Support Grant112025
P30CA016672Cancer Center Support Grant102025
P30CA014520UW Comprehensive Cancer Center Support52025
P30CA013330Cancer Center Support Grant42025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens32025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA021765Cancer Center Support Grant (CCSG)32025
R01DK068634Hematopoietic Regulation via GATA Switches32025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia32025

1 to 10 of 1,108Source NIH's project files

See all 1,108 nih grants

Papers1,824

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Somatic DDX41 mutations confer neomorphic splicing activity in the pathogenesis of myelodysplastic neoplasms.bioRxiv202642818088PubTator, text miningPubMed
Reply to Correspondence: Leveraging paired germline and somatic analysis to improve the classification of DDX41 variants.Br J Haematol202642750255PubTator, text miningPubMed
DDX41 mutations establish a separate entity in acute myeloid leukemia with distinct survival outcomes.Hemasphere202642741445PubTator, text miningPubMed
Circulating Amyloid and Misfolded Biomarkers in Early Myocardial Injury: A Systematic Review and Epistemic Meta-Analysis.Int J Mol Sci202642737853PubTator, text miningPubMed
Age- and sex-adjusted genomic differences between Korean and Beat AML cohorts.Blood Adv202642710088PubTator, text miningPubMed
[Germline DDX41 mutations and myelodysplastic neoplasms].Zhonghua Xue Ye Xue Za Zhi202642706181PubTator, text miningPubMed
Decoding serum C-reactive protein-associated molecular patterns in aging and secondhand smoke exposure chronic obstructive pulmonary disease male patients: evidence from cross-sectional, multi-omic and clinical studies.
Front Med (Lausanne)202642630335PubTator, text miningPubMed
Distinct clinical and genetic characteristics of myelodysplastic syndrome in younger patients.Br J Haematol202642630001PubTator, text miningPubMed
Weekly Metronomic Venetoclax and Decitabine/Cedazuridine in Acute Myeloid Leukemia Patient Declining Blood Transfusion.Case Rep Oncol202642626761PubTator, text miningPubMed
Leveraging paired germline and somatic analysis to improve the classification of DDX41 variants.Br J Haematol202642619431PubTator, text miningPubMed

1 to 10 of 1,824

See all 1,824 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51428

GET https://conductscience.org/api/genes/v1/51428/patents