Gene · 51428
DDX41: DEAD-box helicase 41
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DDX41: DEAD-box helicase 41. Genes, record 51428. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51428
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UJV9 | Probable ATP-dependent RNA helicase DDX41 | 622 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 43315 | Q9UJV9 | Espacenet |
| JP 2024504002 A | 2024-01-30 | 80 | Q9UJV9 | Espacenet |
| JP 2024502755 A | 2024-01-23 | 79 | Q9UJV9 | Espacenet |
| JP 2024500874 A | 2024-01-10 | 80 | Q9UJV9 | Espacenet |
| JP 2024500877 A | 2024-01-10 | 80 | Q9UJV9 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 23000 | Q9UJV9 | Espacenet |
| JP 2022537570 A | 2022-08-26 | 79 | Q9UJV9 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 125971 | Q9UJV9 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 2969 | Q9UJV9 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 223750 | Q9UJV9 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,108
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DDX41 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 5 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 4 | 2025 |
| P01AI063302 | The intersection of innate and adaptive immunity to intracellular pathogens | 3 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 3 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| R01DK068634 | Hematopoietic Regulation via GATA Switches | 3 | 2025 |
| R35CA197695 | Translating genomic discoveries to improved outcomes for high risk acute leukemia | 3 | 2025 |
1 to 10 of 1,108Source NIH's project files
See all 1,108 nih grantsPapers1,824
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Somatic DDX41 mutations confer neomorphic splicing activity in the pathogenesis of myelodysplastic neoplasms. | bioRxiv | 2026 | 42818088 | PubTator, text mining | PubMed |
| Reply to Correspondence: Leveraging paired germline and somatic analysis to improve the classification of DDX41 variants. | Br J Haematol | 2026 | 42750255 | PubTator, text mining | PubMed |
| DDX41 mutations establish a separate entity in acute myeloid leukemia with distinct survival outcomes. | Hemasphere | 2026 | 42741445 | PubTator, text mining | PubMed |
| Circulating Amyloid and Misfolded Biomarkers in Early Myocardial Injury: A Systematic Review and Epistemic Meta-Analysis. | Int J Mol Sci | 2026 | 42737853 | PubTator, text mining | PubMed |
| Age- and sex-adjusted genomic differences between Korean and Beat AML cohorts. | Blood Adv | 2026 | 42710088 | PubTator, text mining | PubMed |
| [Germline DDX41 mutations and myelodysplastic neoplasms]. | Zhonghua Xue Ye Xue Za Zhi | 2026 | 42706181 | PubTator, text mining | PubMed |
Decoding serum C-reactive protein-associated molecular patterns in aging and secondhand smoke exposure chronic obstructive pulmonary disease male patients: evidence from cross-sectional, multi-omic and clinical studies. | Front Med (Lausanne) | 2026 | 42630335 | PubTator, text mining | PubMed |
| Distinct clinical and genetic characteristics of myelodysplastic syndrome in younger patients. | Br J Haematol | 2026 | 42630001 | PubTator, text mining | PubMed |
| Weekly Metronomic Venetoclax and Decitabine/Cedazuridine in Acute Myeloid Leukemia Patient Declining Blood Transfusion. | Case Rep Oncol | 2026 | 42626761 | PubTator, text mining | PubMed |
| Leveraging paired germline and somatic analysis to improve the classification of DDX41 variants. | Br J Haematol | 2026 | 42619431 | PubTator, text mining | PubMed |
1 to 10 of 1,824
See all 1,824 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/51428
GET https://conductscience.org/api/genes/v1/51428/patents