ConductScience.org, home

Gene · 51455

REV1: REV1 DNA directed polymerase

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. REV1: REV1 DNA directed polymerase. Genes, record 51455. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51455

On this page

Gene

Symbol
REV1
HGNC
Name
REV1 DNA directed polymerase
HGNC
NCBI Gene ID
51455
NCBI Gene
HGNC ID
HGNC:14060
HGNC
Ensembl
ENSG00000135945
NCBI Gene
Aliases
AIBP80, REV1L
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UBZ9Translesion synthesis protein REV11,25117Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-291294Q9UBZ9Espacenet
US 12435331 B22025-10-0764Q9UBZ9Espacenet
JP 2025517969 A2025-06-121294Q9UBZ9Espacenet
JP 2024533316 A2024-09-124428Q9UBZ9Espacenet
JP 2024123008 A2024-09-108191Q9UBZ9Espacenet
EP 4399291 A22024-07-174428Q9UBZ9Espacenet
JP 2023113627 A2023-08-1664Q9UBZ9Espacenet
US 11542496 B22023-01-0364Q9UBZ9Espacenet
US 11446398 B22022-09-2073082Q9UBZ9Espacenet
JP 2022524081 A2022-04-27176053Q9UBZ9Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,230

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleREV1 papersNewest fiscal year
P30CA086862Cancer Center Support Grant142025
ZIAHD001500DNA Replication, Repair, and Mutagenesis In Eukaryotic And Prokaryotic Cells142025
P30CA008748Cancer Center Support Grant122025
P30CA016672Cancer Center Support Grant112025
P30ES010126UNC Center for Environmental Health and Susceptibility112025
P01CA092584Structural Cell Biology of DNA Repair Machines92025
P30CA068485Cancer Center Support Grant92025
R01HL052725Molecular Pathogenesis of Fanconi Anemia92025
P30CA016086Cancer Center Support Grant52025
R01CA237263DNA replication stress in cancer52025

1 to 10 of 1,230Source NIH's project files

See all 1,230 nih grants

Papers1,571

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Inhibition of Translesion DNA Synthesis Sensitizes BRCA-Deficient Ovarian Cancer to PARP Inhibitors.Cancer Res202642804161PubTator, text miningPubMed
Structural insight into human Y-family polymerases and mechanistic basis of translesion synthesis of key DNA damages.Mutat Res Rev Mutat Res202642767445PubTator, text miningPubMed
The Oligomeric State of Rad6-Rad18 and Its Interactions with Translesion Synthesis Proteins.Biomolecules202642650838PubTator, text miningPubMed
Targeting MAD2L2-dependent translesion synthesis impairs DNA damage tolerance and enhances cellular response to cisplatin.Front Cell Dev Biol202642591613PubTator, text miningPubMed
Human REV1 interacts with DHX36 to promote replication and tolerance of G-quadruplex DNA.Nucleic Acids Res202642258547PubTator, text miningPubMed
A sibling study of variation in parental mutation rates.bioRxiv202642182135PubTator, text miningPubMed
Targeted tumor starvation strategy augments radiosensitivity and enhances radioactive iodine-mediated tumor immunotherapy.Acta Pharmacol Sin202641781702PubTator, text miningPubMed
Virtual Reality in Chronic Conditions: An Umbrella Review.Nurs Rep202641745882PubTator, text miningPubMed
SEC11A identified as a critical host factor for HMPV through virus-induced alternative splicing.Biosaf Health202641743027PubTator, text miningPubMed
Advancing inducible gene-inactivation systems to explore synthetic lethality.NAR Cancer202641736896PubTator, text miningPubMed

1 to 10 of 1,571

See all 1,571 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51455

GET https://conductscience.org/api/genes/v1/51455/patents?page=2