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ISYNA1: inositol-3-phosphate synthase 1

1 protein, 19 patents, 0 drugs, 0 trials, 3,488 NIH grants and 8,038 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolISYNA1HGNC
Nameinositol-3-phosphate synthase 1HGNC
NCBI Gene ID51477NCBI Gene
HGNC IDHGNC:29821HGNC
EnsemblENSG00000105655NCBI Gene
AliasesINO1, INOS, IPS, IPS 1, IPS-1, Ino1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9NPH2Inositol-3-phosphate synthase 15580Ensembl, GeneID, HGNCUniProt

Patents 19

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449884Q9NPH2Espacenet
JP 2025032204 A2025-03-1130049Q9NPH2Espacenet
EP 4461818 A22024-11-1330049Q9NPH2Espacenet
JP 2023058610 A2023-04-2530049Q9NPH2Espacenet
US 11446398 B22022-09-2040496Q9NPH2Espacenet
JP 2022524081 A2022-04-27143467Q9NPH2Espacenet
JP 2020508652 A2020-03-2630049Q9NPH2Espacenet
JP 2019054813 A2019-04-11230319Q9NPH2Espacenet
US 9952224 B22018-04-2459Q9NPH2Espacenet
JP 2017121241 A2017-07-13230319Q9NPH2Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3488

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant162,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center72,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases72,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support62,025NIH's project files
P30CA016058Cancer Center Support Grant62,025NIH's project files
P30CA023168Cancer Center Support Grant62,025NIH's project files
P30CA068485Cancer Center Support Grant62,025NIH's project files
P01CA116087H. pylori-induced Inflammation and Gastric Cancer52,025NIH's project files
P30CA047904Cancer Center Support Grant52,025NIH's project files

Papers 8038

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42812057PubTator, text miningPubMed
42809111PubTator, text miningPubMed
42808714PubTator, text miningPubMed
42806647PubTator, text miningPubMed
42790655PubTator, text miningPubMed
42789027PubTator, text miningPubMed
42783432PubTator, text miningPubMed
42773389PubTator, text miningPubMed
42772039PubTator, text miningPubMed
42763914PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license