Gene · 51547
SIRT7: sirtuin 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SIRT7: sirtuin 7. Genes, record 51547. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51547
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | 400 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 63672 | Q9NRC8 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5812 | Q9NRC8 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5812 | Q9NRC8 | Espacenet |
| EP 4491229 A2 | 2025-01-15 | 288 | Q9NRC8 | Espacenet |
| WO 2024230934 A1 | 2024-11-14 | 413 | Q9NRC8 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 79453 | Q9NRC8 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 182424 | Q9NRC8 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 10299 | Q9NRC8 | Espacenet |
| WO 2020161342 A1 | 2020-08-13 | 288 | Q9NRC8 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 244107 | Q9NRC8 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,086
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SIRT7 papers | Newest fiscal year |
|---|---|---|---|
| I01BX000286 | Elucidating functions of mammalian SIRT7 deacetylase in aging and disease | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 5 | 2025 |
| ZIAES102205 | Sirtuins and nuclear receptors in aging and age-associated diseases | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 4 | 2025 |
| P30DK056341 | Washington University Nutrition Obesity Research Center | 4 | 2025 |
| T32DK007217 | Diabetes, Endocrinology and Metabolism Training Grant | 4 | 2025 |
| ZIAHL005102 | Metabolic pathways linked to immunity | 4 | 2025 |
| ZIAHL006047 | Role of intracellular organelle homeostasis in adaptation to dietary restrictive interventions | 4 | 2025 |
1 to 10 of 1,086Source NIH's project files
See all 1,086 nih grantsPapers2,721
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Ningxintong and its active component calycosin stabilize vulnerable atherosclerotic plaques by targeting SIRT7 and inhibiting pyroptosis. | Phytomedicine | 2026 | 42815265 | PubTator, text mining | PubMed |
| Computational design of siRNAs targeting SIRT7 in gynaecological cancers with cell-penetrating peptide-based delivery assessment. | Comput Biol Chem | 2026 | 42710143 | PubTator, text mining | PubMed |
| Experimental approaches for investigating sirtuin-mediated mitochondrial function, cellular metabolism, and epigenetic regulation. | Methods Enzymol | 2026 | 42692759 | PubTator, text mining | PubMed |
| Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart. | J Precis Med (Amst) | 2026 | 42644057 | PubTator, text mining | PubMed |
| SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation. | Proc Natl Acad Sci U S A | 2026 | 42636358 | PubTator, text mining | PubMed |
| Deciphering the role of sirtuins in cancer immunoregulation through molecular cross-talk and docking-based interaction. | Mol Biol Rep | 2026 | 42627540 | PubTator, text mining | PubMed |
| Correction to "Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression". | Adv Sci (Weinh) | 2026 | 42615387 | PubTator, text mining | PubMed |
| Protective mechanisms of Sirtuin Family in myocardial ischemia-reperfusion injury and translational therapeutic perspectives. | Mol Biol Rep | 2026 | 42584557 | PubTator, text mining | PubMed |
| Ferroptosis in vitiligo and melanoma: Opposing susceptibilities, shared mechanisms, and therapeutic targets. | Exp Cell Res | 2026 | 42567394 | PubTator, text mining | PubMed |
| Decoding context-dependent sirtuin pharmacology in cancer: Metabolic-epigenetic switches and precision therapeutic targeting. | Crit Rev Oncol Hematol | 2026 | 42543141 | PubTator, text mining | PubMed |
1 to 10 of 2,721
See all 2,721 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/51547
GET https://conductscience.org/api/genes/v1/51547/patents?page=2