ConductScience.org, home

Gene · 51547

SIRT7: sirtuin 7

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. SIRT7: sirtuin 7. Genes, record 51547. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51547

On this page

Gene

Symbol
SIRT7
HGNC
Name
sirtuin 7
HGNC
NCBI Gene ID
51547
NCBI Gene
HGNC ID
HGNC:14935
HGNC
Ensembl
ENSG00000187531
NCBI Gene
Aliases
SIR2L7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NRC8NAD-dependent protein deacetylase sirtuin-74004Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463672Q9NRC8Espacenet
EP 4650780 A22025-11-195812Q9NRC8Espacenet
JP 2025517970 A2025-06-125812Q9NRC8Espacenet
EP 4491229 A22025-01-15288Q9NRC8Espacenet
WO 2024230934 A12024-11-14413Q9NRC8Espacenet
US 11446398 B22022-09-2079453Q9NRC8Espacenet
JP 2022524081 A2022-04-27182424Q9NRC8Espacenet
US 11078247 B22021-08-0310299Q9NRC8Espacenet
WO 2020161342 A12020-08-13288Q9NRC8Espacenet
JP 2019054813 A2019-04-11244107Q9NRC8Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,086

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSIRT7 papersNewest fiscal year
I01BX000286Elucidating functions of mammalian SIRT7 deacetylase in aging and disease72025
P30CA008748Cancer Center Support Grant52025
P30CA016056Roswell Park Cancer Center Support Grant52025
ZIAES102205Sirtuins and nuclear receptors in aging and age-associated diseases52025
P30CA016672Cancer Center Support Grant42025
P30DK020572Michigan Diabetes Research Center (MDRC)42025
P30DK056341Washington University Nutrition Obesity Research Center42025
T32DK007217Diabetes, Endocrinology and Metabolism Training Grant42025
ZIAHL005102Metabolic pathways linked to immunity42025
ZIAHL006047Role of intracellular organelle homeostasis in adaptation to dietary restrictive interventions42025

1 to 10 of 1,086Source NIH's project files

See all 1,086 nih grants

Papers2,721

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Ningxintong and its active component calycosin stabilize vulnerable atherosclerotic plaques by targeting SIRT7 and inhibiting pyroptosis.Phytomedicine202642815265PubTator, text miningPubMed
Computational design of siRNAs targeting SIRT7 in gynaecological cancers with cell-penetrating peptide-based delivery assessment.Comput Biol Chem202642710143PubTator, text miningPubMed
Experimental approaches for investigating sirtuin-mediated mitochondrial function, cellular metabolism, and epigenetic regulation.Methods Enzymol202642692759PubTator, text miningPubMed
Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart.J Precis Med (Amst)202642644057PubTator, text miningPubMed
SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation.Proc Natl Acad Sci U S A202642636358PubTator, text miningPubMed
Deciphering the role of sirtuins in cancer immunoregulation through molecular cross-talk and docking-based interaction.Mol Biol Rep202642627540PubTator, text miningPubMed
Correction to "Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression".Adv Sci (Weinh)202642615387PubTator, text miningPubMed
Protective mechanisms of Sirtuin Family in myocardial ischemia-reperfusion injury and translational therapeutic perspectives.Mol Biol Rep202642584557PubTator, text miningPubMed
Ferroptosis in vitiligo and melanoma: Opposing susceptibilities, shared mechanisms, and therapeutic targets.Exp Cell Res202642567394PubTator, text miningPubMed
Decoding context-dependent sirtuin pharmacology in cancer: Metabolic-epigenetic switches and precision therapeutic targeting.Crit Rev Oncol Hematol202642543141PubTator, text miningPubMed

1 to 10 of 2,721

See all 2,721 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51547

GET https://conductscience.org/api/genes/v1/51547/patents?page=2