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PDGFB: platelet derived growth factor subunit B

1 protein, 317 patents, 1 drug, 18 trials, 5,324 NIH grants and 10,580 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPDGFBHGNC
Nameplatelet derived growth factor subunit BHGNC
NCBI Gene ID5155NCBI Gene
HGNC IDHGNC:8800HGNC
EnsemblENSG00000100311NCBI Gene
AliasesIBGC5, PDGF-2, PDGF2, SIS, SSV, c-sisNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01127Platelet-derived growth factor subunit B2416Ensembl, GeneID, HGNCUniProt

Patents 317

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4830719 A22026-10-283P01127Espacenet
JP 2026094314 A2026-06-0967P01127Espacenet
JP 2026090361 A2026-06-023P01127Espacenet
EP 4705273 A22026-03-11258P01127Espacenet
JP 2026021360 A2026-02-10158P01127Espacenet
WO 2026030380 A22026-02-052P01127Espacenet
JP 2026500184 A2026-01-062P01127Espacenet
JP 2025538460 A2025-11-287P01127Espacenet
EP 4650780 A22025-11-195854P01127Espacenet
WO 2025225410 A2025-10-3013P01127Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
PEGPLERANIB SODIUMCHEMBL3301576Platelet-derived growth factor subunit B inhibitorINHIBITORChEMBL

Trials 18

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02859441PEGPLERANIB SODIUMPHASE1/PHASE22020-07-14ClinicalTrials.gov
NCT02591914PEGPLERANIB SODIUMPHASE1ClinicalTrials.gov
NCT02387957PEGPLERANIB SODIUMPHASE22019-03-05ClinicalTrials.gov
NCT02214628PEGPLERANIB SODIUMPHASE22019-07-10ClinicalTrials.gov
NCT02081339PEGPLERANIB SODIUMClinicalTrials.gov
NCT01944839PEGPLERANIB SODIUMPHASE32018-08-10ClinicalTrials.gov
NCT01940900PEGPLERANIB SODIUMPHASE32018-08-15ClinicalTrials.gov
NCT01940887PEGPLERANIB SODIUMPHASE32020-09-30ClinicalTrials.gov
NCT01281098PEGPLERANIB SODIUMPHASE2ClinicalTrials.gov
NCT01245387PEGPLERANIB SODIUM2011-01-07ClinicalTrials.gov

NIH grants 5324

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant502,025NIH's project files
P30CA008748Cancer Center Support Grant482,025NIH's project files
P30CA006973Regional Oncology Research Center132,025NIH's project files
P30DK084567Mayo Center for Cell Signaling in Gastroenterology132,025NIH's project files
P30CA043703Case Comprehensive Cancer Center Support Grant112,025NIH's project files
P30CA068485Cancer Center Support Grant102,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award102,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant92,025NIH's project files
P50CA127001SPORE in Brain Cancer92,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant72,025NIH's project files

Papers 10580

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42787653PubTator, text miningPubMed
42781159PubTator, text miningPubMed
42736498PubTator, text miningPubMed
42722664PubTator, text miningPubMed
42700318PubTator, text miningPubMed
42695089PubTator, text miningPubMed
42688036PubTator, text miningPubMed
42687923PubTator, text miningPubMed
42674819PubTator, text miningPubMed
42667331PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license