Gene · 51564
HDAC7: histone deacetylase 7
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HDAC7: histone deacetylase 7. Genes, record 51564. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51564
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8WUI4 | Histone deacetylase 7 | 952 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 13283 | Q8WUI4 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 15079 | Q8WUI4 | Espacenet |
| EP 4626460 A1 | 2025-10-08 | 10 | Q8WUI4 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 15079 | Q8WUI4 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 13283 | Q8WUI4 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6487 | Q8WUI4 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 38631 | Q8WUI4 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 141602 | Q8WUI4 | Espacenet |
| US 10501513 B2 | 2019-12-10 | 6487 | Q8WUI4 | Espacenet |
| JP 2017197545 A | 2017-11-02 | 31188 | Q8WUI4 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs12
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| ABEXINOSTAT | CHEMBL2103863 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| BELINOSTAT | CHEMBL408513 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| CUDC-101 | CHEMBL598797 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| ENTINOSTAT | CHEMBL27759 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| FIMEPINOSTAT | CHEMBL3622533 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| GIVINOSTAT | CHEMBL1213492 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| GIVINOSTAT HYDROCHLORIDE | CHEMBL6068400 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| PANOBINOSTAT | CHEMBL483254 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| PANOBINOSTAT LACTATE | CHEMBL3545368 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
| QUISINOSTAT | CHEMBL2105763 | Histone deacetylase inhibitor | INHIBITOR | ChEMBL |
1 to 10 of 12
See all 12 drugsTrials389
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07492394 | ENTINOSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT07441486 | ENTINOSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT07330544 | ENTINOSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT07261592 | ENTINOSTAT | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT07235618 | ENTINOSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT06824662 | QUISINOSTAT | EARLY_PHASE1 | ClinicalTrials.gov | |
| NCT06769633 | GIVINOSTAT HYDROCHLORIDE | PHASE2 | ClinicalTrials.gov | |
| NCT06561048 | BELINOSTAT | PHASE3 | ClinicalTrials.gov | |
| NCT06406465 | BELINOSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT06240520 | PANOBINOSTAT | PHASE1/PHASE2 | ClinicalTrials.gov |
1 to 10 of 389
See all 389 trialsNIH grants1,540
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HDAC7 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 14 | 2025 |
| R01GM049758 | Structure and Function of Metalloenzymes | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P30CA043703 | Case Comprehensive Cancer Center Support Grant | 9 | 2025 |
| R01HL095524 | Modulation of Lung Disease by Genetic/Epigenetic Profiling | 6 | 2025 |
| P30DK084567 | Mayo Center for Cell Signaling in Gastroenterology | 5 | 2025 |
| R35GM131821 | Chemical Approaches to Study Protein Post-translational Modifications | 5 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 3 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
1 to 10 of 1,540Source NIH's project files
See all 1,540 nih grantsPapers2,197
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Comparative transcriptomics analysis of histone deacetylases, transcription factors, and ion channel genes in human iPSC-cardiomyocytes vs. the adult human heart. | J Precis Med (Amst) | 2026 | 42644057 | PubTator, text mining | PubMed |
| Histone Deacetylase 7 protects against pathologic cardiac hypertrophy. | J Mol Cell Cardiol | 2026 | 42250622 | PubTator, text mining | PubMed |
| HDAC7-Induced Epigenetic Repression Modulates ATF3 Functional Plasticity in Colorectal Cancer Pathogenesis. | Int J Biol Sci | 2026 | 42157949 | PubTator, text mining | PubMed |
| Epigenetic remodeling of the nasal epithelium in chronic rhinosinusitis: Histone deacetylase 7 (HDAC7) mediates type 2 inflammation. | Ann Allergy Asthma Immunol | 2026 | 42103401 | PubTator, text mining | PubMed |
| EGFR-19del nuclear translocation increases HDAC7 expression inhibiting the Hippo pathway and exacerbating TKI resistance in lung adenocarcinoma. | Theranostics | 2026 | 42094614 | PubTator, text mining | PubMed |
| Altered HDAC expression is associated with CYP24A1-mediated vitamin D deficiency in gestational diabetes mellitus. | Epigenomics | 2026 | 42089337 | PubTator, text mining | PubMed |
| USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review). | Int J Mol Med | 2026 | 41891958 | PubTator, text mining | PubMed |
| Global molecular landscape of early MASLD progression in human obesity. | Elife | 2026 | 41870035 | PubTator, text mining | PubMed |
| HDAC7 is a key factor for the germinal center reaction and its underexpression is associated with DLBCL prognosis. | J Immunol | 2026 | 41847858 | PubTator, text mining | PubMed |
| Growth factor applications and clinical translation: advances and challenges. | Ann Med | 2026 | 41837883 | PubTator, text mining | PubMed |
1 to 10 of 2,197
See all 2,197 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/51564
GET https://conductscience.org/api/genes/v1/51564/patents?page=2