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PDGFRB: platelet derived growth factor receptor beta

1 protein, 214 patents, 51 drugs, 3,070 trials, 10,798 NIH grants and 25,496 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPDGFRBHGNC
Nameplatelet derived growth factor receptor betaHGNC
NCBI Gene ID5159NCBI Gene
HGNC IDHGNC:8804HGNC
EnsemblENSG00000113721NCBI Gene
AliasesCD140B, CD140b, IBGC4, IMF1, JTK12, KOGS, OPDKD, PDGFR, PDGFR-1, PDGFR1, PENTTNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P09619Platelet-derived growth factor receptor beta1,1068Ensembl, GeneID, HGNCUniProt

Patents 214

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4830719 A22026-10-2815P09619Espacenet
JP 2026120541 A2026-07-2255P09619Espacenet
JP 2026094314 A2026-06-0955P09619Espacenet
JP 2026090361 A2026-06-0215P09619Espacenet
JP 2026082857 A2026-05-1955P09619Espacenet
JP 2026021360 A2026-02-10146P09619Espacenet
WO 2025259600 A22025-12-1847P09619Espacenet
EP 4650780 A22025-11-191963P09619Espacenet
EP 4641202 A22025-10-2995P09619Espacenet
EP 4641203 A22025-10-2960P09619Espacenet

Drugs 51

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BECAPLERMINCHEMBL1201556Platelet-derived growth factor receptor agonistAGONISTChEMBL
CATEQUENTINIBCHEMBL4303201Platelet-derived growth factor receptor beta inhibitorINHIBITORChEMBL
CDP-860CHEMBL2109544Platelet-derived growth factor receptor beta inhibitorINHIBITORChEMBL
CEDIRANIBCHEMBL491473Platelet-derived growth factor receptor inhibitorINHIBITORChEMBL
CEP-2563CHEMBL6069183Platelet-derived growth factor receptor beta inhibitorINHIBITORChEMBL
CEP-2563 DIHYDROCHLORIDECHEMBL6067987Platelet-derived growth factor receptor beta inhibitorINHIBITORChEMBL
CM-082CHEMBL3545427Platelet-derived growth factor receptor beta inhibitorINHIBITORChEMBL
CRENOLANIBCHEMBL2105728Platelet-derived growth factor receptor inhibitorINHIBITORChEMBL
DASATINIB ANHYDROUSCHEMBL1421Platelet-derived growth factor receptor beta inhibitorINHIBITORChEMBL
DOVITINIBCHEMBL522892Platelet-derived growth factor receptor inhibitorINHIBITORChEMBL

Trials 3070

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07602101CATEQUENTINIBPHASE2ClinicalTrials.gov
NCT07583589NINTEDANIBPHASE2ClinicalTrials.gov
NCT07581821CATEQUENTINIBPHASE2ClinicalTrials.gov
NCT07572695SORAFENIBClinicalTrials.gov
NCT07572695MIDOSTAURINClinicalTrials.gov
NCT07562581CATEQUENTINIBPHASE2ClinicalTrials.gov
NCT07559864REGORAFENIBPHASE2ClinicalTrials.gov
NCT07559370IMATINIBPHASE2ClinicalTrials.gov
NCT07545213CATEQUENTINIBPHASE2ClinicalTrials.gov
NCT07540390CATEQUENTINIBPHASE3ClinicalTrials.gov

NIH grants 10798

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant3042,025NIH's project files
P30CA008748Cancer Center Support Grant1792,025NIH's project files
P30CA006973Regional Oncology Research Center652,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)612,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase362,025NIH's project files
P30CA016058Cancer Center Support Grant362,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant362,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant342,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award332,025NIH's project files
P30CA068485Cancer Center Support Grant312,025NIH's project files

Papers 25496

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42810192PubTator, text miningPubMed
42797458PubTator, text miningPubMed
42793349PubTator, text miningPubMed
42792247PubTator, text miningPubMed
42781857PubTator, text miningPubMed
42781159PubTator, text miningPubMed
42780569PubTator, text miningPubMed
42773186PubTator, text miningPubMed
42764425PubTator, text miningPubMed
42764248PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license