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Gene · 5172

SLC26A4: solute carrier family 26 member 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC26A4: solute carrier family 26 member 4. Genes, record 5172. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5172

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Gene

Symbol
SLC26A4
HGNC
Name
solute carrier family 26 member 4
HGNC
NCBI Gene ID
5172
NCBI Gene
HGNC ID
HGNC:8818
HGNC
Ensembl
ENSG00000091137
NCBI Gene
Aliases
DFNB4, EVA, PDS, TDH2B
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O43511Pendrin7800Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026041707 A2026-03-106O43511Espacenet
JP 2026004568 A2026-01-1464350O43511Espacenet
EP 4641201 A22025-10-2924684O43511Espacenet
JP 2025529142 A2025-09-044115O43511Espacenet
EP 4594508 A22025-08-0610O43511Espacenet
US 12371689 B22025-07-294115O43511Espacenet
JP 2025517969 A2025-06-1224684O43511Espacenet
EP 4565703 A22025-06-114O43511Espacenet
KR 1020250080886 A2025-06-0510O43511Espacenet
KR 1020250059407 A2025-05-024O43511Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,040

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC26A4 papersNewest fiscal year
R01DC012049Optimizing Genetic Testing for Deafness for Clinical Diagnostics192025
R01DC003594Identification of Autosomal Recessive Nonsyndromic Hearing Impairment Genes182025
P30DK034854Integrated Epithelial and Muscosal Biology162025
R01DC009645A Collaborative Search for New Genes for Non-Syndromic Deafness142025
ZIADC000039Identification of Genes Causing Syndromic and Nonsyndromic Hearing Impairment122025
ZIADC000064Clinical Analysis of Disorders of Hearing and Balance122025
ZIADC000048Functional Studies of "Deafness Genes" Essential for Hearing82025
P30DK054759Precision Medicine Center for Cystic Fibrosis72025
P30ES005605Environmental Health Sciences Research Center62025
R01DK015070Thyroid Physiology Studies of Inherited Disorders62025

1 to 10 of 1,040Source NIH's project files

See all 1,040 nih grants

Papers3,149

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Thyroid hormone synthesis and AITD-related inflammatory factors are modulated during early pregnancy in ewes.Theriogenology202742790002PubTator, text miningPubMed
A novel variant c.1185_1196dup (p.(Gly396_Ser399dup)) in the SLC26A4 gene associated with recessive hearing loss.Vavilovskii Zhurnal Genet Selektsii202642824106PubTator, text miningPubMed
Repurposing approved drugs as Pendrin (SLC26A4) inhibitors in allergic asthma: single-cell nomination, structure-based screening and functional validation.Front Pharmacol202642812201PubTator, text miningPubMed
Unilateral enlarged vestibular aqueduct syndrome: clinical profiles, SLC26A4 mutations, and the diagnostic utility of the ASNR waveform.Acta Otolaryngol202642771488PubTator, text miningPubMed
Mutation Spectrum and Novel Rare Variants in a Han Chinese Hearing Loss Cohort Using a Tiered Sequencing Strategy.Mol Genet Genomic Med202642764263PubTator, text miningPubMed
Audiological Features in Pendred Syndrome: A Scoping Review.J Int Adv Otol202642732627PubTator, text miningPubMed
Genetic Heterogeneity in Susceptibility to Familial Thyroid Nodular Disease.Thyroid202642723469PubTator, text miningPubMed
Maternal Gestational Diabetes Mellitus as an Independent Risk Factor for Hearing Impairment in Hyperbilirubinemia Newborns: A Prospective Birth Cohort With Genetic Profiling.Noise Health202642684354PubTator, text miningPubMed
ERK Signaling in Thyroid Cancer: Lineage Suppression, Epigenetic Reprogramming, and Theranostic Reversal.Cancers (Basel)202642650008PubTator, text miningPubMed
Potential sublimating exocomets around the young star PDS 70.Nat Commun202642637760PubTator, text miningPubMed

1 to 10 of 3,149

See all 3,149 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5172

GET https://conductscience.org/api/genes/v1/5172/patents?page=2