Gene · 5172
SLC26A4: solute carrier family 26 member 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SLC26A4: solute carrier family 26 member 4. Genes, record 5172. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5172
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O43511 | Pendrin | 780 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents42
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026041707 A | 2026-03-10 | 6 | O43511 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 64350 | O43511 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 24684 | O43511 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 4115 | O43511 | Espacenet |
| EP 4594508 A2 | 2025-08-06 | 10 | O43511 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 4115 | O43511 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 24684 | O43511 | Espacenet |
| EP 4565703 A2 | 2025-06-11 | 4 | O43511 | Espacenet |
| KR 1020250080886 A | 2025-06-05 | 10 | O43511 | Espacenet |
| KR 1020250059407 A | 2025-05-02 | 4 | O43511 | Espacenet |
1 to 10 of 42
See all 42 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,040
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SLC26A4 papers | Newest fiscal year |
|---|---|---|---|
| R01DC012049 | Optimizing Genetic Testing for Deafness for Clinical Diagnostics | 19 | 2025 |
| R01DC003594 | Identification of Autosomal Recessive Nonsyndromic Hearing Impairment Genes | 18 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 16 | 2025 |
| R01DC009645 | A Collaborative Search for New Genes for Non-Syndromic Deafness | 14 | 2025 |
| ZIADC000039 | Identification of Genes Causing Syndromic and Nonsyndromic Hearing Impairment | 12 | 2025 |
| ZIADC000064 | Clinical Analysis of Disorders of Hearing and Balance | 12 | 2025 |
| ZIADC000048 | Functional Studies of "Deafness Genes" Essential for Hearing | 8 | 2025 |
| P30DK054759 | Precision Medicine Center for Cystic Fibrosis | 7 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 6 | 2025 |
| R01DK015070 | Thyroid Physiology Studies of Inherited Disorders | 6 | 2025 |
1 to 10 of 1,040Source NIH's project files
See all 1,040 nih grantsPapers3,149
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Thyroid hormone synthesis and AITD-related inflammatory factors are modulated during early pregnancy in ewes. | Theriogenology | 2027 | 42790002 | PubTator, text mining | PubMed |
| A novel variant c.1185_1196dup (p.(Gly396_Ser399dup)) in the SLC26A4 gene associated with recessive hearing loss. | Vavilovskii Zhurnal Genet Selektsii | 2026 | 42824106 | PubTator, text mining | PubMed |
| Repurposing approved drugs as Pendrin (SLC26A4) inhibitors in allergic asthma: single-cell nomination, structure-based screening and functional validation. | Front Pharmacol | 2026 | 42812201 | PubTator, text mining | PubMed |
| Unilateral enlarged vestibular aqueduct syndrome: clinical profiles, SLC26A4 mutations, and the diagnostic utility of the ASNR waveform. | Acta Otolaryngol | 2026 | 42771488 | PubTator, text mining | PubMed |
| Mutation Spectrum and Novel Rare Variants in a Han Chinese Hearing Loss Cohort Using a Tiered Sequencing Strategy. | Mol Genet Genomic Med | 2026 | 42764263 | PubTator, text mining | PubMed |
| Audiological Features in Pendred Syndrome: A Scoping Review. | J Int Adv Otol | 2026 | 42732627 | PubTator, text mining | PubMed |
| Genetic Heterogeneity in Susceptibility to Familial Thyroid Nodular Disease. | Thyroid | 2026 | 42723469 | PubTator, text mining | PubMed |
| Maternal Gestational Diabetes Mellitus as an Independent Risk Factor for Hearing Impairment in Hyperbilirubinemia Newborns: A Prospective Birth Cohort With Genetic Profiling. | Noise Health | 2026 | 42684354 | PubTator, text mining | PubMed |
| ERK Signaling in Thyroid Cancer: Lineage Suppression, Epigenetic Reprogramming, and Theranostic Reversal. | Cancers (Basel) | 2026 | 42650008 | PubTator, text mining | PubMed |
| Potential sublimating exocomets around the young star PDS 70. | Nat Commun | 2026 | 42637760 | PubTator, text mining | PubMed |
1 to 10 of 3,149
See all 3,149 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5172
GET https://conductscience.org/api/genes/v1/5172/patents?page=2