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Gene · 5173

PDYN: prodynorphin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PDYN: prodynorphin. Genes, record 5173. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5173

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Gene

Symbol
PDYN
HGNC
Name
prodynorphin
HGNC
NCBI Gene ID
5173
NCBI Gene
HGNC ID
HGNC:8820
HGNC
Ensembl
ENSG00000101327
NCBI Gene
Aliases
ADCA, PENKB, SCA23
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P01213Proenkephalin-B2548Ensembl, GeneID, HGNC

Source UniProt

Patents59

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1459085P01213Espacenet
JP 2026004568 A2026-01-1459086P01213Espacenet
JP 2026004568 A2026-01-1459087P01213Espacenet
EP 4650780 A22025-11-19386P01213Espacenet
EP 4641201 A22025-10-29273P01213Espacenet
JP 2025147176 A2025-10-0610234P01213Espacenet
JP 2025147176 A2025-10-0610235P01213Espacenet
JP 2025147176 A2025-10-0610236P01213Espacenet
JP 2025532800 A2025-10-031P01213Espacenet
JP 2025529142 A2025-09-047317P01213Espacenet

1 to 10 of 59

See all 59 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,512

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePDYN papersNewest fiscal year
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).142025
R28AA012725Brain Tissue Resource Center for Alcohol Research132025
P60AA006420CNS Effects of Alcohol: Cellular Neurobiology72025
ZIAAA000301Integrative genetics of behavior with high throughput technologies72025
R01MH063266Roles of nuleus accumbens CREB and Kappa function in depression62025
P30DA018310Neurometabolomics and Neuroproteomics Center on Cell-Cell Signaling42025
P50AA012870Center for the Translational Neuroscience of Alcoholism42025
P50AA017823Developmental Exposure Alcohol Research Center32025
T32DA007027Training in the pharmacology of abused drugs32025
P20GM103476Mississippi INBRE22025

1 to 10 of 1,512Source NIH's project files

See all 1,512 nih grants

Papers1,714

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exploring candidate biomarkers for nonobstructive azoospermia: A bioinformatics and machine learning approach.Sci Prog202642709486PubTator, text miningPubMed
Molecular Ontology Predicts Output Connections From the Nucleus of the Solitary Tract.J Comp Neurol202642561032PubTator, text miningPubMed
When memory shapes appetite: A top-down peptidergic gate for context-dependent feeding.Neuron202642235488PubTator, text miningPubMed
Investigation of the Relationship Between Prodynorphin Gene Polymorphisms and Sensory Differences in Children With Autism Spectrum Disorder.Int J Dev Neurosci202641886646PubTator, text miningPubMed
Epigenetic Repression of the Serotonergic Neuron Phenotype Following Adolescent Binge Drinking Is Restored through Inhibition of Proinflammatory Signaling by Exercise and Glycyrrhizic Acid.J Neurosci202641839571PubTator, text miningPubMed
A novel mucosa-associated lymphoid tissue translocation gene 1-related immune prognostic signature and targeted drug screening for glioblastoma.Brain Circ202641815811PubTator, text miningPubMed
Cyclover-Assisted Liquid-Phase Peptide Synthesis Using T3P® as a Green Coupling Reagent.Org Lett202641733902PubTator, text miningPubMed
A Multimodal Single-Cell Epigenomic and 3D Genome Atlas of the Human Basal Ganglia.bioRxiv202641726865PubTator, text miningPubMed
A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding.Neuron202641687615PubTator, text miningPubMed
Group A streptococcal PerR coordinates iron and zinc homeostasis through Dpr, aiding in bacterial fitness during endothelial cell infection.mSystems202641586523PubTator, text miningPubMed

1 to 10 of 1,714

See all 1,714 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5173

GET https://conductscience.org/api/genes/v1/5173/patents?page=2