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Gene · 51744

CD244: CD244 molecule

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CD244: CD244 molecule. Genes, record 51744. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/51744

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Gene

Symbol
CD244
HGNC
Name
CD244 molecule
HGNC
NCBI Gene ID
51744
NCBI Gene
HGNC ID
HGNC:18171
HGNC
Ensembl
ENSG00000122223
NCBI Gene
Aliases
2B4, NAIL, NKR2B4, Nmrk, SLAMF4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BZW8Natural killer cell receptor 2B43700Ensembl, GeneID, HGNC

Source UniProt

Patents102

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4806462 A22026-09-1640Q9BZW8Espacenet
EP 4795154 A12026-08-26109Q9BZW8Espacenet
EP 4680651 A12026-01-2169Q9BZW8Espacenet
JP 2026004568 A2026-01-1440506Q9BZW8Espacenet
JP 2025541179 A2025-12-18126Q9BZW8Espacenet
JP 2025181929 A2025-12-11280Q9BZW8Espacenet
EP 4650780 A22025-11-198351Q9BZW8Espacenet
EP 4641202 A22025-10-29462Q9BZW8Espacenet
EP 4641203 A22025-10-29245Q9BZW8Espacenet
EP 4630459 A12025-10-15126Q9BZW8Espacenet

1 to 10 of 102

See all 102 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,389

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCD244 papersNewest fiscal year
P30CA016672Cancer Center Support Grant352025
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy222025
P30CA008748Cancer Center Support Grant202025
P01CA111412NK cells, their receptors and cancer therapy182025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies172025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital162025
P30CA006927Comprehensive Cancer Center Program at Fox Chase112025
P30CA016520Abramson Cancer Center Support Grant102025
P30AI027763UCSF-Bay Area Center for AIDS Research92025
T32AI007290Molecular and Cellular Immunobiology92025

1 to 10 of 2,389Source NIH's project files

See all 2,389 nih grants

Papers3,665

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Alternative splicing of CD244 restrains natural killer cells at the maternal-fetal interface.Mucosal Immunol202642805341PubTator, text miningPubMed
Dual targeting of CD244 and CD2 by a viral-immunoevasin-guided engineered CD48-Fc mutant for T- and NK-cell modulation.Front Immunol202642746293PubTator, text miningPubMed
Could the Immune Modulation of Invariant Natural Killer T Cell and the Expression of CD244 and CD196 on Natural Killer Cell Subtypes Impact the Treatment Outcomes of Acute Myeloid Leukemia Patients?J Hematol202642730131PubTator, text miningPubMed
Impact of Gestational Maternal SARS-CoV-2 Infection on Neonatal Inflammatory Biomarkers.Am J Reprod Immunol202642640037PubTator, text miningPubMed
Irradiated CD19 chimeric antigen receptor YTS cells retain antitumor activity and offer a scalable alternative to autologous CAR-T therapy.Haematologica202642610426PubTator, text miningPubMed
Exploring the Causal Role of Circulating Inflammatory Proteins in Multiple Sclerosis: A Mendelian Randomization Study and Druggability Analysis.Curr Neurovasc Res202642517387PubTator, text miningPubMed
Dual Regulatory Functions and Therapeutic Potential of CD48 in Tumor Immunity.Oncol Res202642500566PubTator, text miningPubMed
CD244 overexpression indicates NK cell dysfunction and tumor progression in diffuse large B-cell lymphoma.Front Immunol202642483169PubTator, text miningPubMed
Inflammatory Cytokines May Mediate the Causal Relationship between Metabolites and Primary Sclerosing Cholangitis: A Bidirectional Mediation Mendelian Randomization Study.Curr Med Chem202642337887PubTator, text miningPubMed
A blueberry-derived polysaccharide inhibits SARS-CoV-2 papain-like protease and exhibits broad-spectrum anti-coronavirus activity.Nat Prod Res202642262732PubTator, text miningPubMed

1 to 10 of 3,665

See all 3,665 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/51744

GET https://conductscience.org/api/genes/v1/51744/patents?page=2