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CDK12: cyclin dependent kinase 12
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Gene · 51755

Papers3,441

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

101 to 120 of 3,441

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TitleJournalYearPMIDFound bySource
From Serendipity to Strategy: Rationalizing Molecular Glue Discovery and Proximity-Induced Pharmacology through Chemical Biology.J Am Chem Soc202641622634PubTator, text miningPubMed
Targeting PKMYT1 enhances antitumor immune responses to PD-L1 blockade in castration-resistant prostate cancer.J Immunother Cancer202641617394PubTator, text miningPubMed
Intronic polyadenylation-derived long noncoding RNA modulates nucleolar integrity and function.Proc Natl Acad Sci U S A202641615750PubTator, text miningPubMed
CDK12 paradox in breast Cancer: Loss-of-Function fusion and oncogenic amplification as dual therapeutic Targets.Hum Pathol202641577204PubTator, text miningPubMed
Assessing the Detection Power of Genome-Wide Copy Number Variation Profiles in Prostate Cancer Using Simulated Shallow Whole-Genome Sequencing Data.JCO Clin Cancer Inform202641576301PubTator, text miningPubMed
Cervical HPV-independent adenosquamous carcinoma: report of a case series.Virchows Arch202641569320PubTator, text miningPubMed
Transcription termination counteracts DNA damage after WEE1 inhibition.Nucleic Acids Res202641569153PubTator, text miningPubMed
Domain adaptation, self-supervision, and generative augmentation enhance GNNs for breast cancer prediction.Sci Rep202641559366PubTator, text miningPubMed
Oxidative stress-driven transcriptomic remodeling in human astrocytes reveals network signatures associated with neurodegenerative and cardiovascular processes.Comput Struct Biotechnol J202641550140PubTator, text miningPubMed
A tailored histology-driven molecular profiling algorithm proposal for salivary gland cancers.ESMO Open202641547215PubTator, text miningPubMed
Isovanillin regulates gastric cancer cells apoptosis and metastasis by targeting ROS-mediated MAPK and PI3K signaling pathways.Anticancer Drugs202641546559PubTator, text miningPubMed
Therapeutic targeting of CDK12: a medicinal chemistry perspective.Bioorg Med Chem202641544426PubTator, text miningPubMed
Gemogenovatucel-T Advantage in Clonal Tumor Mutation Burden-High Ovarian Cancer.JCO Precis Oncol202641533999PubTator, text miningPubMed
Assessing the association between homologous recombination deficiency scores and treatment response in localized and metastatic prostate cancer.J Pathol Clin Res202641532774PubTator, text miningPubMed
RE: Targeting CDK12 disrupts estrogen-receptor chromatin recruitment and ER-MED1 transcription in advanced ER+ breast cancer.J Natl Cancer Inst202641507084PubTator, text miningPubMed
First-in-Class Quinoline-Dione-Derived PROTACs: Potent Degraders of Cdc25 Phosphatases for Antitumor Therapy.J Med Chem202641507075PubTator, text miningPubMed
CDK12 and CDK13 in oncology: from RNA regulation to therapeutic targeting.Cell Oncol (Dordr)202641491919PubTator, text miningPubMed
Characteristics of Germline and Somatic Mutations of DNA Repair Genes in Korean Men with Prostate Cancer.World J Mens Health202641430472PubTator, text miningPubMed
Targeting CDK12 rescues C/EBPβ-mediated platinum and PARP inhibitor resistance in ovarian cancer.Cell Signal202641412562PubTator, text miningPubMed
Spatial molecular analyses reveal key features associated with response to KN026 in advanced HER2-positive breast cancer.Br J Cancer202641366063PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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