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SERPINF1: serpin family F member 1

1 protein, 121 patents, 0 drugs, 0 trials, 2,216 NIH grants and 4,674 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSERPINF1HGNC
Nameserpin family F member 1HGNC
NCBI Gene ID5176NCBI Gene
HGNC IDHGNC:8824HGNC
EnsemblENSG00000132386NCBI Gene
AliasesEPC-1, OI12, OI6, PEDF, PIG35NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P36955Pigment epithelium-derived factor4183Ensembl, GeneID, HGNCUniProt

Patents 121

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463228P36955Espacenet
EP 4667578 A22025-12-24217P36955Espacenet
EP 4667578 A22025-12-24218P36955Espacenet
EP 4650780 A22025-11-191509P36955Espacenet
EP 4640699 A22025-10-2910P36955Espacenet
JP 2025147176 A2025-10-0612102P36955Espacenet
JP 2025131621 A2025-09-09217P36955Espacenet
JP 2025131621 A2025-09-09218P36955Espacenet
JP 2025529142 A2025-09-047690P36955Espacenet
US 12371689 B22025-07-297690P36955Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2216

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAEY000306Role of Protein Interactions in Retina Development and Function352,025NIH's project files
P30EY016665Core Grant for Vision Research152,025NIH's project files
R01EY005121RPE Messengers, Transcription and Photoreceptor Renewal142,025NIH's project files
P30EY001792P30 Core Grant for Vision Research132,025NIH's project files
P30EY005722Center Core Grant for Vision Research122,025NIH's project files
P30EY006360P30-Core Grant for Vision Research122,025NIH's project files
P30DK034989Yale Liver Center112,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support102,025NIH's project files
P30EY000331Vision Research Core at UCLA82,025NIH's project files
R01EY019309A new pathogenic mechanism for diabetic retinopathy82,025NIH's project files

Papers 4674

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42800007PubTator, text miningPubMed
42735794PubTator, text miningPubMed
42700741PubTator, text miningPubMed
42700360PubTator, text miningPubMed
42687870PubTator, text miningPubMed
42527138PubTator, text miningPubMed
42511631PubTator, text miningPubMed
42473035PubTator, text miningPubMed
42459926PubTator, text miningPubMed
42443978PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license