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Gene · 5184

PEPD: peptidase D

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PEPD: peptidase D. Genes, record 5184. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5184

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Gene

Symbol
PEPD
HGNC
Name
peptidase D
HGNC
NCBI Gene ID
5184
NCBI Gene
HGNC ID
HGNC:8840
HGNC
Ensembl
ENSG00000124299
NCBI Gene
Aliases
PROLIDASE
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P12955Xaa-Pro dipeptidase49321Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19305P12955Espacenet
JP 2026004568 A2026-01-1457270P12955Espacenet
EP 4650780 A22025-11-191116P12955Espacenet
EP 4641201 A22025-10-29787P12955Espacenet
JP 2025517969 A2025-06-12787P12955Espacenet
JP 2025517970 A2025-06-121116P12955Espacenet
WO 2024214081 A12024-10-17305P12955Espacenet
JP 2022141755 A2022-09-29239P12955Espacenet
US 11446398 B22022-09-2061761P12955Espacenet
JP 2022527082 A2022-05-3030P12955Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants810

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePEPD papersNewest fiscal year
P30CA016056Roswell Park Cancer Center Support Grant92025
P30CA008748Cancer Center Support Grant72025
R01AI137168Characterizing the Mechanism of DPP8/9 Inhibitor-Induced Pyroptosis52025
R01AI163170Redox control of the NLRP1 inflammasome52025
P30DK063491Diabetes Research Center (DRC)42025
R01CA266478Prolidase Inhibitors as Therapeutic Agents for Acute Myeloid Leukemia42025
R01DK093757Genetic epidemiology of rare and regulatory variants for metabolic traits42025
ZIAHG000024Genetic analysis of type II diabetes42025
P30DK056350Nutrition Obesity Research Center (NORC)32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025

1 to 10 of 810Source NIH's project files

See all 810 nih grants

Papers1,375

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dimethyl phthalate disrupts sulfur cycling and triggers toxic H2S pollution in sludge anaerobic system.Environ Res202642822631PubTator, text miningPubMed
Balancing automation and expertise: real-world evaluation of AI-assisted whole-exome sequencing in lupus-causing genes.Lupus Sci Med202642816061PubTator, text miningPubMed
An Investigation to Study Morphology, Nanomechanical Attributes, Transcriptomics, and Proteomics of Tumor Associated Macrophages Derived Extracellular Vesicles in the Tumor Microenvironment.J Anal Oncol202642719843PubTator, text miningPubMed
Establishment of human induced pluripotent stem cell lines and isogenic gene-corrected controls from three patients with prolidase deficiency.Stem Cell Res202642673728PubTator, text miningPubMed
[Biomarkers in tear fluid in keratoconus].Vestn Oftalmol202642608928PubTator, text miningPubMed
Mechanistic drivers of thermogenic adipose tissue dysfunction in aging and obesity.Am J Physiol Endocrinol Metab202642606522PubTator, text miningPubMed
Interstitial Lung Disease in Children: Rare Genetic Variants Beyond Surfactant Dysfunction.Pediatr Pulmonol202642598967PubTator, text miningPubMed
Corneal Findings in a Patient With Prolidase Deficiency: A Multimodal Imaging Characterization.Cornea202642551919PubTator, text miningPubMed
Pharmacogenomics of antipsychotic-induced weight gain: A systematic review.Schizophr Res202642480244PubTator, text miningPubMed
Tremella fuciformis Extract Evokes Similar Effect as Hyaluronic Acid on Wound Healing but Through Different Mechanisms in Human Dermal Fibroblasts.Molecules202642451721PubTator, text miningPubMed

1 to 10 of 1,375

See all 1,375 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5184

GET https://conductscience.org/api/genes/v1/5184/patents?page=2