ConductScience.org, home

Library / Genes

PF4: platelet factor 4

1 protein, 144 patents, 0 drugs, 0 trials, 3,411 NIH grants and 10,485 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPF4HGNC
Nameplatelet factor 4HGNC
NCBI Gene ID5196NCBI Gene
HGNC IDHGNC:8861HGNC
EnsemblENSG00000163737NCBI Gene
AliasesCXCL4, PF-4, SCYB4NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P02776Platelet factor 410110Ensembl, GeneID, HGNCUniProt

Patents 144

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11359P02776Espacenet
JP 2026004568 A2026-01-1458126P02776Espacenet
JP 2025172140 A2025-11-209P02776Espacenet
EP 4650780 A22025-11-193678P02776Espacenet
JP 2025147176 A2025-10-0610258P02776Espacenet
JP 2025147176 A2025-10-0616703P02776Espacenet
JP 2025529142 A2025-09-047324P02776Espacenet
WO 2025178079 A2025-08-282P02776Espacenet
US 12371689 B22025-07-297324P02776Espacenet
JP 2025099926 A2025-07-033P02776Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3411

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant152,025NIH's project files
R01HL158932New approaches to the pathophysiology, diagnosis and management of heparin-induced thrombocytopenia132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award122,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
P30ES001247Environmental Agents as Modulators of Disease Processes102,025NIH's project files
T32HL007057Hematology & Transfusion Medicine92,025NIH's project files
I01CX001696Platelet Reprogramming During Inflammation72,025NIH's project files
P42ES004705Toxic substances in the environment72,025NIH's project files
R01HL151730Complement and thrombosis in HIT72,025NIH's project files
P30CA043703Case Comprehensive Cancer Center Support Grant62,025NIH's project files

Papers 10485

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42811375PubTator, text miningPubMed
42807460PubTator, text miningPubMed
42792830PubTator, text miningPubMed
42792218PubTator, text miningPubMed
42788303PubTator, text miningPubMed
42769966PubTator, text miningPubMed
42751187PubTator, text miningPubMed
42739654PubTator, text miningPubMed
42736613PubTator, text miningPubMed
42728255PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license