ConductScience.org, home

Gene · 5214

PFKP: phosphofructokinase, platelet

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PFKP: phosphofructokinase, platelet. Genes, record 5214. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5214

On this page

Gene

Symbol
PFKP
HGNC
Name
phosphofructokinase, platelet
HGNC
NCBI Gene ID
5214
NCBI Gene
HGNC ID
HGNC:8878
HGNC
Ensembl
ENSG00000067057
NCBI Gene
Aliases
ATP-PFK, PFK-C, PFK-P, PFKF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q01813ATP-dependent 6-phosphofructokinase, platelet type7847Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026022479 A12026-01-293Q01813Espacenet
JP 2026004568 A2026-01-1457816Q01813Espacenet
EP 4650780 A22025-11-1910408Q01813Espacenet
EP 4641201 A22025-10-2910735Q01813Espacenet
JP 2025147176 A2025-10-0610261Q01813Espacenet
JP 2025529142 A2025-09-047326Q01813Espacenet
US 12371689 B22025-07-297326Q01813Espacenet
JP 2025517969 A2025-06-1210735Q01813Espacenet
JP 2025517970 A2025-06-1210408Q01813Espacenet
JP 2025032204 A2025-03-1133344Q01813Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,246

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePFKP papersNewest fiscal year
P30CA016672Cancer Center Support Grant122025
P30CA008748Cancer Center Support Grant92025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes42025
P30CA016042Cancer Center Support Grant42025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control42025
R01CA157644Central tolerance mechanisms in B-cell malignancies42025
R35CA197628Metabolic gatekeepers in B-cell malignancies42025
P30CA062203Cancer Center Support Grant32025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025
P30DK026743UCSF Liver Center32025

1 to 10 of 1,246Source NIH's project files

See all 1,246 nih grants

Papers1,761

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metagenomic Insights into Microbial Functional Potential Associated with Soil Carbon, Nitrogen, and Phosphorus Cycling Along an Elevational Gradient in a Warm-Temperate Forest.Microorganisms202642795596PubTator, text miningPubMed
Recombinant human SGK3 protein hydrogel: a novel therapeutic strategy for myocardial repair in ischemia/reperfusion injury.Acta Biochim Biophys Sin (Shanghai)202642744988PubTator, text miningPubMed
Transcriptomics and single-cell RNA sequencing uncover prognostic characteristics and immune regulatory mechanisms of lactylation in cervical cancer.Bioimpacts202642666969PubTator, text miningPubMed
Proteomics combined with single-cell sequencing reveals key genes and computational lead compound related to ligamentum flavum hypertrophy, lactate metabolism and lactate modification.Biochem Biophys Res Commun202642632329PubTator, text miningPubMed
Integrated analysis of enzymes, mRNAs, and miRNAs provides insight into the regulatory potential of extracellular vesicles in recipient cell glucose metabolism.Front Bioinform202642630526PubTator, text miningPubMed
Metabolic-epigenetic reprogramming via the PLOD1-PFKP axis drives cisplatin resistance in HNSCC.Acta Pharm Sin B202642592154PubTator, text miningPubMed
MFN2 inhibits colorectal cancer tumorigenesis by regulating glycolysis through TRIM21-mediated PFKP stability.Mol Immunol202642541838PubTator, text miningPubMed
Integrated multi-omics and SHAP analysis reveal the core mechanisms of metabolic reprogramming in lung adenocarcinoma.Discov Oncol202642472421PubTator, text miningPubMed
PFKP promotes oncogenesis in osteosarcoma through PI3K/HIF-1α pathway-mediated H3K18la modification.Cell Signal202642425209PubTator, text miningPubMed
PFKP: A biomarker for prognosis, response to treatment and immune function of breast cancer.Int J Biol Markers202642394480PubTator, text miningPubMed

1 to 10 of 1,761

See all 1,761 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5214

GET https://conductscience.org/api/genes/v1/5214/patents?page=2