Gene · 5214
PFKP: phosphofructokinase, platelet
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PFKP: phosphofructokinase, platelet. Genes, record 5214. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5214
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q01813 | ATP-dependent 6-phosphofructokinase, platelet type | 784 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents50
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026022479 A1 | 2026-01-29 | 3 | Q01813 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 57816 | Q01813 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10408 | Q01813 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10735 | Q01813 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10261 | Q01813 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7326 | Q01813 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7326 | Q01813 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10735 | Q01813 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10408 | Q01813 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 33344 | Q01813 | Espacenet |
1 to 10 of 50
See all 50 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,246
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PFKP papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 4 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 4 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 4 | 2025 |
| R01CA157644 | Central tolerance mechanisms in B-cell malignancies | 4 | 2025 |
| R35CA197628 | Metabolic gatekeepers in B-cell malignancies | 4 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| P30DK026743 | UCSF Liver Center | 3 | 2025 |
1 to 10 of 1,246Source NIH's project files
See all 1,246 nih grantsPapers1,761
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Metagenomic Insights into Microbial Functional Potential Associated with Soil Carbon, Nitrogen, and Phosphorus Cycling Along an Elevational Gradient in a Warm-Temperate Forest. | Microorganisms | 2026 | 42795596 | PubTator, text mining | PubMed |
| Recombinant human SGK3 protein hydrogel: a novel therapeutic strategy for myocardial repair in ischemia/reperfusion injury. | Acta Biochim Biophys Sin (Shanghai) | 2026 | 42744988 | PubTator, text mining | PubMed |
| Transcriptomics and single-cell RNA sequencing uncover prognostic characteristics and immune regulatory mechanisms of lactylation in cervical cancer. | Bioimpacts | 2026 | 42666969 | PubTator, text mining | PubMed |
| Proteomics combined with single-cell sequencing reveals key genes and computational lead compound related to ligamentum flavum hypertrophy, lactate metabolism and lactate modification. | Biochem Biophys Res Commun | 2026 | 42632329 | PubTator, text mining | PubMed |
| Integrated analysis of enzymes, mRNAs, and miRNAs provides insight into the regulatory potential of extracellular vesicles in recipient cell glucose metabolism. | Front Bioinform | 2026 | 42630526 | PubTator, text mining | PubMed |
| Metabolic-epigenetic reprogramming via the PLOD1-PFKP axis drives cisplatin resistance in HNSCC. | Acta Pharm Sin B | 2026 | 42592154 | PubTator, text mining | PubMed |
| MFN2 inhibits colorectal cancer tumorigenesis by regulating glycolysis through TRIM21-mediated PFKP stability. | Mol Immunol | 2026 | 42541838 | PubTator, text mining | PubMed |
| Integrated multi-omics and SHAP analysis reveal the core mechanisms of metabolic reprogramming in lung adenocarcinoma. | Discov Oncol | 2026 | 42472421 | PubTator, text mining | PubMed |
| PFKP promotes oncogenesis in osteosarcoma through PI3K/HIF-1α pathway-mediated H3K18la modification. | Cell Signal | 2026 | 42425209 | PubTator, text mining | PubMed |
| PFKP: A biomarker for prognosis, response to treatment and immune function of breast cancer. | Int J Biol Markers | 2026 | 42394480 | PubTator, text mining | PubMed |
1 to 10 of 1,761
See all 1,761 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5214
GET https://conductscience.org/api/genes/v1/5214/patents?page=2