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PGA5: pepsinogen A5

1 protein, 32 patents, 1 drug, 6 trials, 1,120 NIH grants and 8,199 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPGA5HGNC
Namepepsinogen A5HGNC
NCBI Gene ID5222NCBI Gene
HGNC IDHGNC:8887HGNC
EnsemblENSG00000256713NCBI Gene
AliasesPg5NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P0DJD9Pepsin A-53880Ensembl, GeneID, HGNCUniProt

Patents 32

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457260P0DJD9Espacenet
JP 2026004568 A2026-01-1457263P0DJD9Espacenet
EP 4650780 A22025-11-194629P0DJD9Espacenet
EP 4641201 A22025-10-294194P0DJD9Espacenet
JP 2025147176 A2025-10-0610279P0DJD9Espacenet
JP 2025529142 A2025-09-047330P0DJD9Espacenet
US 12391935 B22025-08-197P0DJD9Espacenet
WO 2025162587 A12025-08-0734P0DJD9Espacenet
US 12371689 B22025-07-297330P0DJD9Espacenet
JP 2025517969 A2025-06-124194P0DJD9Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
SUCRALFATECHEMBL6067980Pepsin A inhibitorINHIBITORChEMBL

Trials 6

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07540026SUCRALFATEClinicalTrials.gov
NCT06617026SUCRALFATEPHASE1/PHASE2ClinicalTrials.gov
NCT06421389SUCRALFATEClinicalTrials.gov
NCT03241030SUCRALFATEPHASE22021-10-29ClinicalTrials.gov
NCT02353078SUCRALFATEEARLY_PHASE1ClinicalTrials.gov
NCT00814359SUCRALFATEPHASE3ClinicalTrials.gov

NIH grants 1120

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant52,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase32,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)32,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases32,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease32,025NIH's project files
ZIABC010348Protein Structure32,025NIH's project files
ZIAHD000256Collagen-related diseases32,025NIH's project files
I01BX000930Oxyntic Atrophy and Novel Gastric Lineages.22,025NIH's project files
P30CA008748Cancer Center Support Grant22,025NIH's project files
P30CA013148Comprehensive Cancer Center Support Grant22,025NIH's project files

Papers 8199

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
40637051PubTator, text miningPubMed
40061120PubTator, text miningPubMed
39740967PubTator, text miningPubMed
39154467PubTator, text miningPubMed
38917150PubTator, text miningPubMed
38905834PubTator, text miningPubMed
38599159PubTator, text miningPubMed
38368754PubTator, text miningPubMed
38249638PubTator, text miningPubMed
38187077PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license