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Gene · 5226

PGD: phosphogluconate dehydrogenase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PGD: phosphogluconate dehydrogenase. Genes, record 5226. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5226

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Gene

Symbol
PGD
HGNC
Name
phosphogluconate dehydrogenase
HGNC
NCBI Gene ID
5226
NCBI Gene
HGNC ID
HGNC:8891
HGNC
Ensembl
ENSG00000142657
NCBI Gene
Aliases
6PGD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P522096-phosphogluconate dehydrogenase, decarboxylating4834Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457837P52209Espacenet
EP 4650780 A22025-11-192757P52209Espacenet
EP 4641201 A22025-10-292334P52209Espacenet
EP 4626460 A12025-10-081P52209Espacenet
WO 2025142929 A2025-07-0310P52209Espacenet
JP 2025517969 A2025-06-122334P52209Espacenet
JP 2025517970 A2025-06-122757P52209Espacenet
JP 2025081326 A2025-05-2751P52209Espacenet
WO 2025068276 A22025-04-0384P52209Espacenet
JP 2024005979 A2024-01-1716P52209Espacenet

1 to 10 of 38

See all 38 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants756

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePGD papersNewest fiscal year
R01CA140515Signaling importance of ‘functionless’ lyso-PAF, an inactive form of platelet activating factor, in melanoma with mutant Nras92025
R01CA222594The Evolution of PGD Addiction in Human Pancreatic Cancer42025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes32025
P30CA016520Abramson Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA138292Winship Cancer Institute Cancer Center Support Grant32025
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant32025
P30ES006694Southwest Environmental Health Sciences Center32025
T32EB009380Training in Multi-scale Analysis of Biological Structure and Function32025
P30CA023168Cancer Center Support Grant22025

1 to 10 of 756Source NIH's project files

See all 756 nih grants

Papers3,346

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Malate synthesis in the chloroplasts of C3 plants.Curr Opin Plant Biol202642475967PubTator, text miningPubMed
iTRAQ- and MRM-Based Proteomics Identify Early Injury Biomarkers for Primary Dysfunction After Liver Transplantation.Ann Transplant202642444103PubTator, text miningPubMed
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with elevated mean corpuscular volume (MCV) and bilirubin.BMC Genom Data202642115943PubTator, text miningPubMed
Glucose-6-phosphate dehydrogenase deficiency and the risk of developing systemic lupus erythematosus.Front Med (Lausanne)202642078437PubTator, text miningPubMed
Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities.J Biomed Sci202641928257PubTator, text miningPubMed
mTOR signaling regulates demand-adapted hematopoiesis and metabolic reprogramming required for an effective cellular immune response in Drosophila melanogaster larvae.PLoS Genet202641875141PubTator, text miningPubMed
Circular and Long Non-Coding RNAs in Cancer Metabolism: Dual Perspective of Biomarkers and Therapeutic Targets.Noncoding RNA202641874139PubTator, text miningPubMed
Reassessing Transketolase Assays: Methodological Considerations for Detecting Functional Thiamine Deficiency.Ann N Y Acad Sci202641870883PubTator, text miningPubMed
ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbances.Cell Death Discov202641866403PubTator, text miningPubMed
Metabolic reprogramming in cancer: dysregulation of glucose, lipid, and amino acid pathways and therapeutic opportunities.Mol Biomed202641806079PubTator, text miningPubMed

1 to 10 of 3,346

See all 3,346 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5226

GET https://conductscience.org/api/genes/v1/5226/patents?page=2