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PGR: progesterone receptor

1 protein, 57 patents, 34 drugs, 763 trials, 16,123 NIH grants and 76,184 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPGRHGNC
Nameprogesterone receptorHGNC
NCBI Gene ID5241NCBI Gene
HGNC IDHGNC:8910HGNC
EnsemblENSG00000082175NCBI Gene
AliasesNR3C3, PRNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06401Progesterone receptor93320Ensembl, GeneID, HGNCUniProt

Patents 57

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-295228P06401Espacenet
JP 2025147176 A2025-10-0615481P06401Espacenet
JP 2025147176 A2025-10-0616598P06401Espacenet
JP 2025517969 A2025-06-125228P06401Espacenet
JP 2025032204 A2025-03-1133361P06401Espacenet
JP 2025028160 A2025-02-2815481P06401Espacenet
JP 2025028160 A2025-02-2816598P06401Espacenet
KR 1020250010750 A2025-01-2115481P06401Espacenet
KR 1020250010750 A2025-01-2116598P06401Espacenet
EP 4461818 A22024-11-1333361P06401Espacenet

Drugs 34

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ALLYLESTRENOLCHEMBL3185133Progesterone receptor agonistAGONISTChEMBL
ASOPRISNILCHEMBL267431Progesterone receptor modulatorMODULATORChEMBL
CHLORMADINONE ACETATECHEMBL110691Progesterone receptor modulatorMODULATORChEMBL
CYPROTERONE ACETATECHEMBL139835Progesterone receptor agonistAGONISTChEMBL
DANAZOLCHEMBL1479Progesterone receptor agonistAGONISTChEMBL
DESOGESTRELCHEMBL1533Progesterone receptor agonistAGONISTChEMBL
DROSPIRENONECHEMBL1509Progesterone receptor agonistAGONISTChEMBL
DYDROGESTERONECHEMBL1200853Progesterone receptor agonistAGONISTChEMBL
ETHYNODIOL DIACETATECHEMBL1200624Progesterone receptor agonistAGONISTChEMBL
ETONOGESTRELCHEMBL1531Progesterone receptor agonistAGONISTChEMBL

Trials 763

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07536763DROSPIRENONEPHASE3ClinicalTrials.gov
NCT07513480CYPROTERONE ACETATEClinicalTrials.gov
NCT07508657PROGESTERONEPHASE4ClinicalTrials.gov
NCT07488949MEDROXYPROGESTERONE ACETATEClinicalTrials.gov
NCT07477808MEGESTROL ACETATEPHASE3ClinicalTrials.gov
NCT07436793PROGESTERONEPHASE2ClinicalTrials.gov
NCT07436793MEGESTROL ACETATEPHASE2ClinicalTrials.gov
NCT07419776NORGESTRELClinicalTrials.gov
NCT07409792PROGESTERONEClinicalTrials.gov
NCT07409792DYDROGESTERONEClinicalTrials.gov

NIH grants 16123

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant6752,025NIH's project files
P30CA016672Cancer Center Support Grant6272,025NIH's project files
P50CA058223SPORE in Breast Cancer2012,025NIH's project files
P50CA116201Mayo Clinic Breast Cancer SPORE1692,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant1392,025NIH's project files
P30CA016086Cancer Center Support Grant1312,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility1252,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant1182,025NIH's project files
P30CA068485Cancer Center Support Grant1172,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant1162,025NIH's project files

Papers 76184

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825662PubTator, text miningPubMed
42825327PubTator, text miningPubMed
42824934PubTator, text miningPubMed
42823971PubTator, text miningPubMed
42822240PubTator, text miningPubMed
42819586PubTator, text miningPubMed
42818332PubTator, text miningPubMed
42818207PubTator, text miningPubMed
42812609PubTator, text miningPubMed
42812550PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license