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ABCB1: ATP binding cassette subfamily B member 1

1 protein, 56 patents, 5 drugs, 24 trials, 11,552 NIH grants and 57,214 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolABCB1HGNC
NameATP binding cassette subfamily B member 1HGNC
NCBI Gene ID5243NCBI Gene
HGNC IDHGNC:40HGNC
EnsemblENSG00000085563NCBI Gene
AliasesABC20, CD243, CLCS, ENPAT, GP170, MDR1, P-GP, P-gp, PGY1, p-170NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P08183ATP-dependent translocase ABCB11,28024Ensembl, GeneID, HGNCUniProt

Patents 56

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026041756 A52026-05-14330P08183Espacenet
EP 4641201 A22025-10-292105P08183Espacenet
EP 4641202 A22025-10-29124P08183Espacenet
JP 2025147176 A2025-10-0616595P08183Espacenet
JP 2025529142 A2025-09-04187P08183Espacenet
US 12371689 B22025-07-29187P08183Espacenet
JP 2025517969 A2025-06-122105P08183Espacenet
JP 2025062604 A2025-04-147635P08183Espacenet
JP 2025062604 A2025-04-147638P08183Espacenet
JP 2025028160 A2025-02-2816595P08183Espacenet

Drugs 5

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BIRICODARCHEMBL350775P-glycoprotein 1 inhibitorINHIBITORChEMBL
ENCEQUIDARCHEMBL4594298P-glycoprotein 1 inhibitorINHIBITORChEMBL
TARIQUIDARCHEMBL348475P-glycoprotein 1 inhibitorINHIBITORChEMBL
VALSPODARCHEMBL1086218P-glycoprotein 1 inhibitorINHIBITORChEMBL
ZOSUQUIDARCHEMBL444172P-glycoprotein 1 inhibitorINHIBITORChEMBL

Trials 24

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06835400ENCEQUIDARPHASE3ClinicalTrials.gov
NCT04603066TARIQUIDARPHASE1/PHASE22025-08-14ClinicalTrials.gov
NCT03165955ENCEQUIDARPHASE12020-07-08ClinicalTrials.gov
NCT00233909ZOSUQUIDARPHASE1/PHASE2ClinicalTrials.gov
NCT00129168ZOSUQUIDARPHASE1/PHASE2ClinicalTrials.gov
NCT00071058TARIQUIDARPHASE22012-09-12ClinicalTrials.gov
NCT00069160TARIQUIDARPHASE22012-10-12ClinicalTrials.gov
NCT00048633TARIQUIDARPHASE2ClinicalTrials.gov
NCT00042315TARIQUIDARPHASE3ClinicalTrials.gov
NCT00042302TARIQUIDARPHASE3ClinicalTrials.gov

NIH grants 11552

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1652,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)1442,025NIH's project files
ZIABC010030Biochemical Analysis of Multidrug Resistance-linked Transport Proteins1372,025NIH's project files
P30CA008748Cancer Center Support Grant1152,025NIH's project files
ZIABC005598Genetic Analysis of the Multidrug Resistance Phenotype in Tumor Cells672,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant512,025NIH's project files
P30AI050410The University of North Carolina Center for AIDS Research412,025NIH's project files
P30CA006973Regional Oncology Research Center412,025NIH's project files
P30CA016058Cancer Center Support Grant412,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA372,025NIH's project files

Papers 57214

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827146PubTator, text miningPubMed
42821374PubTator, text miningPubMed
42817101PubTator, text miningPubMed
42816037PubTator, text miningPubMed
42811266PubTator, text miningPubMed
42807991PubTator, text miningPubMed
42805149PubTator, text miningPubMed
42804787PubTator, text miningPubMed
42799003PubTator, text miningPubMed
42797784PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license