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Gene · 5252

PHF1: PHD finger protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PHF1: PHD finger protein 1. Genes, record 5252. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5252

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Gene

Symbol
PHF1
HGNC
Name
PHD finger protein 1
HGNC
NCBI Gene ID
5252
NCBI Gene
HGNC ID
HGNC:8919
HGNC
Ensembl
ENSG00000112511
NCBI Gene
Aliases
MTF2L2, PCL1, TDRD19C, hPHF1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O43189PHD finger protein 156710Ensembl, GeneID, HGNC

Source UniProt

Patents9

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457487O43189Espacenet
US 11446398 B22022-09-2062229O43189Espacenet
JP 2022524081 A2022-04-27165200O43189Espacenet
WO 2020043864 A12020-03-051837O43189Espacenet
JP 2019054813 A2019-04-11237922O43189Espacenet
JP 2017121241 A2017-07-13237922O43189Espacenet
JP 2015516143 A2015-06-08237922O43189Espacenet
EP 2052088 A22009-04-2915423O43189Espacenet
EP 2052088 A22009-04-2915427O43189Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,236

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePHF1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant362025
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study172025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions162025
T32AG000255Training in age related neurodegenerative diseases142025
P50CA217694SPORE in Soft Tissue Sarcoma122025
P30AG072979Penn Alzheimer's Disease Research Center (ADRC)112025
P30AG066444Alzheimer's Disease Research Center102025
R01AG032611Clearance and In Vivo Detection of Tau Pathology102025
R01NS077239Epitope-Specific Targeting of Tau Aggregates102025
P30AG062421Massachusetts Alzheimer's Disease Research Center (MADRC)82025

1 to 10 of 2,236Source NIH's project files

See all 2,236 nih grants

Papers3,204

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model.Int J Mol Med202642825350PubTator, text miningPubMed
The Tibial Tubercle-Trochlear Groove Distance Has Higher Accuracy and Moderate Inter-observer Reliability Compared With the Tibial Tubercle-Roman Arch and Tibial Tubercle-Midepicondyle Distances.Arthroscopy202642732093PubTator, text miningPubMed
Differential Arterial Supply of the ACL and PCL Revealed by 7T-qMRI, Histology, and Micro-CT.Orthop J Sports Med202642668771PubTator, text miningPubMed
Rearfoot striking is associated with lower modeled ACL loading during overground running: a musculoskeletal modeling study.Front Sports Act Living202642625820PubTator, text miningPubMed
Overcoming Limitations in Tibial Tubercle-Trochlear Groove Distance Measurement: A Study of Its Reproducibility and Reliability in High-Grade Trochlear Dysplasia.Orthop J Sports Med202642558718PubTator, text miningPubMed
Degradable porous PLGA/PCL membrane enable a lung alveoli-on-a-chip for modeling particulate-induced alveolar injury.Biofabrication202642546767PubTator, text miningPubMed
Biodegradable poly(ε-caprolactone)/poly(silyl fumarate) shape memory scaffolds.Polymer (Guildf)202642454340PubTator, text miningPubMed
Finite element musculoskeletal modelling of cruciate ligament contact and its effect on knee joint kinematics and biomechanics.Biomech Model Mechanobiol202642436340PubTator, text miningPubMed
Recalibrating PTSD Screening and Prediction: A Pragmatic Agenda to Reduce Missed Cases, False Alarms and Model Hype.J Eval Clin Pract202642340123PubTator, text miningPubMed
SynCAR platform for capturing neuronal synaptic proteopathic seeds.iScience202642325569PubTator, text miningPubMed

1 to 10 of 3,204

See all 3,204 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5252

GET https://conductscience.org/api/genes/v1/5252/grants?page=2