ConductScience.org, home

Library / Genes

SERPINA1: serpin family A member 1

1 protein, 596 patents, 0 drugs, 0 trials, 8,180 NIH grants and 23,491 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSERPINA1HGNC
Nameserpin family A member 1HGNC
NCBI Gene ID5265NCBI Gene
HGNC IDHGNC:8941HGNC
EnsemblENSG00000197249NCBI Gene
AliasesA1A, A1AT, AAT, PI, PI1, PRO2275, alpha-1-antitrypsin, alpha1AT, nNIFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01009Alpha-1-antitrypsin41846Ensembl, GeneID, HGNCUniProt

Patents 596

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4743578 A22026-05-20600P01009Espacenet
US 12630824 B22026-05-191P01009Espacenet
EP 4728067 A22026-04-22427P01009Espacenet
JP 2026067851 A2026-04-21407P01009Espacenet
EP 4705336 A12026-03-111P01009Espacenet
EP 4705462 A22026-03-1179P01009Espacenet
JP 2026027383 A2026-02-183P01009Espacenet
EP 4650780 A22025-11-197213P01009Espacenet
JP 2025170240 A2025-11-1820P01009Espacenet
JP 2025169942 A2025-11-141254P01009Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8180

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant252,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease242,025NIH's project files
T32HL007427SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASES212,025NIH's project files
P30CA016672Cancer Center Support Grant182,025NIH's project files
P30ES005605Environmental Health Sciences Research Center162,025NIH's project files
U01DK062453Colorado Center of Childhood Liver Disease ResearchNetwork162,025NIH's project files
P30DK052574Host-environment interactions in the pathophysiology of digestive disease152,025NIH's project files
P30DK054759Precision Medicine Center for Cystic Fibrosis152,025NIH's project files
R01AI015614Pathogenesis of Fever in Man152,025NIH's project files
P01HL114501Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers142,025NIH's project files

Papers 23491

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823318PubTator, text miningPubMed
42818404PubTator, text miningPubMed
42805959PubTator, text miningPubMed
42793048PubTator, text miningPubMed
42791912PubTator, text miningPubMed
42790593PubTator, text miningPubMed
42784350PubTator, text miningPubMed
42779859PubTator, text miningPubMed
42779858PubTator, text miningPubMed
42763829PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license