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Gene · 5266

PI3: peptidase inhibitor 3

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. PI3: peptidase inhibitor 3. Genes, record 5266. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/5266

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
PI3
HGNC
Name
peptidase inhibitor 3
HGNC
NCBI Gene ID
5266
NCBI Gene
HGNC ID
HGNC:8947
HGNC
Ensembl
ENSG00000124102
NCBI Gene
Aliases
ELAFIN, ESI, SKALP, WAP3, WFDC14, cementoin
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P19957Elafin1173Ensembl, GeneID, HGNC

Source UniProt

Patents95

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457273P19957Espacenet
JP 2026000906 A2026-01-06288P19957Espacenet
EP 4650780 A22025-11-191105P19957Espacenet
JP 2025147176 A2025-10-0610328P19957Espacenet
JP 2025529142 A2025-09-047342P19957Espacenet
US 12371689 B22025-07-297342P19957Espacenet
JP 2025517970 A2025-06-121105P19957Espacenet
JP 2025028160 A2025-02-2810328P19957Espacenet
KR 1020250012200 A2025-01-2311P19957Espacenet
KR 1020250010750 A2025-01-2110328P19957Espacenet

1 to 10 of 95

See all 95 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,330

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant352025
P30CA008748Cancer Center Support Grant292025
P30CA023108Cancer Center Support Grant142025
P01CA039542Cellular and Molecular Studies of Bone Marrow Transplant132025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success112025
P30AR075049Northwestern University Skin Biology and Diseases Resource-based Center72025
P30AI117970District of Columbia Center for AIDS Research62025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202862025
R01HL056470Neonatal Modulation of Airway Contractility62025
P30AI027767UAB Center for AIDS Research (CFAR)52025

1 to 10 of 2,330Source NIH's project files

See all 2,330 nih grants

Papers4,558

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42708167PubTator, text miningPubMed
42699267PubTator, text miningPubMed
42693785PubTator, text miningPubMed
42575868PubTator, text miningPubMed
42566032PubTator, text miningPubMed
42544681PubTator, text miningPubMed
42484178PubTator, text miningPubMed
42377328PubTator, text miningPubMed
42353104PubTator, text miningPubMed
42301613PubTator, text miningPubMed

1 to 10 of 4,558

See all 4,558 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5266

GET https://conductscience.org/api/genes/v1/5266/patents?page=2