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Gene · 5284

PIGR: polymeric immunoglobulin receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PIGR: polymeric immunoglobulin receptor. Genes, record 5284. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5284

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Gene

Symbol
PIGR
HGNC
Name
polymeric immunoglobulin receptor
HGNC
NCBI Gene ID
5284
NCBI Gene
HGNC ID
HGNC:8968
HGNC
Ensembl
ENSG00000162896
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P01833Polymeric immunoglobulin receptor76416Ensembl, GeneID, HGNC

Source UniProt

Patents131

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4801965 A12026-09-09135P01833Espacenet
EP 4727978 A22026-04-22128P01833Espacenet
US 12600801 B22026-04-1444P01833Espacenet
JP 2026502759 A2026-01-275P01833Espacenet
JP 2026004568 A2026-01-1458510P01833Espacenet
US 12486336 B22025-12-0287P01833Espacenet
EP 4650780 A22025-11-197303P01833Espacenet
US 12458704 B22025-11-0447P01833Espacenet
EP 4641201 A22025-10-297255P01833Espacenet
WO 2025217069 A12025-10-1647P01833Espacenet

1 to 10 of 131

See all 131 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,492

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePIGR papersNewest fiscal year
R01DK078244Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes92025
P30CA043703Case Comprehensive Cancer Center Support Grant62025
P30DK034854Integrated Epithelial and Muscosal Biology62025
P30DK058404Molecular and Cellular Basis for Digestive Diseases62025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital52025
R01CA124515Crosstalk between butyrophilins and gamma delta T cells in human cancer52025
R01EY011386Microtubule-based Transport in Lacrimal Gland Function52025
I01BX002378Mechanisms driving airway inflammation in chronic lung disease42025
P30CA008748Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025

1 to 10 of 1,492Source NIH's project files

See all 1,492 nih grants

Papers2,361

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multiomic analysis of malignant ascites defines RORC-expressing dendritic cells at sites of metastasis.Sci Immunol202642826173PubTator, text miningPubMed
Immunohistochemical Detection, In Situ Distribution, and Comparison of Tuft Cells and Other Selected Components of Mucosal Immunity in Nasal Turbinates of Piglets Challenged with Rotavirus from Sows Fed Vitamin A-Deficient Diets with or Without Vitamin A Supplementation.
Vet Sci202642798020PubTator, text miningPubMed
Integrated plasma proteomic and metabolomic profiling demonstrated specific proteins and bile acids remodeling after liver transplantation of children with biliary atresia.Biochim Biophys Acta Proteins Proteom202642777789PubTator, text miningPubMed
Combined association of genetic predisposition and healthy lifestyle with lung cancer risk: a population-based cohort study.Transl Lung Cancer Res202642723677PubTator, text miningPubMed
TFPI-high myofibroblast states and a meta-program-related five-gene prognostic signature in breast cancer.Biomol Biomed202642721217PubTator, text miningPubMed
Large-Scale Plasma Proteomics Reveals Preclinical Biomarkers of Incident Severe Liver Disease.Proteomics Clin Appl202642717724PubTator, text miningPubMed
Proteomic insights into goat milk serum proteins at varying altitudes in China.Food Chem X202642668543PubTator, text miningPubMed
Plasma Proteins Associated With the Immune Response to Anthracycline Cardiotoxicity in Patients With Hematologic Malignancies.Circ Heart Fail202642657460PubTator, text miningPubMed
Aggrecan and polymeric immunoglobulin receptor in extracellular vesicles of patients with seropositive rheumatoid arthritis.J Transl Autoimmun202642502362PubTator, text miningPubMed
Hematopoyetic deficiency in polymeric immunoglobulin receptor attenuates experimental atherosclerosis.Clin Investig Arterioscler202642502048PubTator, text miningPubMed

1 to 10 of 2,361

See all 2,361 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5284

GET https://conductscience.org/api/genes/v1/5284/patents?page=2