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PIK3C2A: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

1 protein, 23 patents, 0 drugs, 0 trials, 1,823 NIH grants and 5,815 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPIK3C2AHGNC
Namephosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alphaHGNC
NCBI Gene ID5286NCBI Gene
HGNC IDHGNC:8971HGNC
EnsemblENSG00000011405NCBI Gene
AliasesCPK, OCSKD, PI3-K-C2(ALPHA), PI3-K-C2A, PI3K-C2-alpha, PI3K-C2alphaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O00443Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha1,6868Ensembl, GeneID, HGNCUniProt

Patents 23

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192541O00443Espacenet
EP 4641201 A22025-10-292129O00443Espacenet
JP 2025517969 A2025-06-122129O00443Espacenet
JP 2025517970 A2025-06-122541O00443Espacenet
JP 2024123008 A2024-09-107617O00443Espacenet
US 11446398 B22022-09-2062751O00443Espacenet
JP 2022524081 A2022-04-27165722O00443Espacenet
KR 1020210128370 A2021-10-2632O00443Espacenet
KR 1020210125457 A2021-10-187O00443Espacenet
US 11078247 B22021-08-038474O00443Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 1823

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant172,025NIH's project files
P30CA016672Cancer Center Support Grant72,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase52,025NIH's project files
P30CA047904Cancer Center Support Grant52,025NIH's project files
P30CA006973Regional Oncology Research Center42,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)42,025NIH's project files
R01CA142746Subcellular enzyme-instructed self-assembly for molecular anticancer nanomedicines42,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award42,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant32,025NIH's project files
P30CA091842Cancer Center Support Grant32,025NIH's project files

Papers 5815

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42644035PubTator, text miningPubMed
42613846PubTator, text miningPubMed
42600511PubTator, text miningPubMed
42576558PubTator, text miningPubMed
42572231PubTator, text miningPubMed
42512883PubTator, text miningPubMed
42470348PubTator, text miningPubMed
42413352PubTator, text miningPubMed
42410791PubTator, text miningPubMed
42381084PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license