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PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3

1 protein, 31 patents, 0 drugs, 0 trials, 2,720 NIH grants and 4,970 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPIK3C3HGNC
Namephosphatidylinositol 3-kinase catalytic subunit type 3HGNC
NCBI Gene ID5289NCBI Gene
HGNC IDHGNC:8974HGNC
EnsemblENSG00000078142NCBI Gene
AliasesVPS34, Vps34, hVps34NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q8NEB9Phosphatidylinositol 3-kinase catalytic subunit type 388741Ensembl, GeneID, HGNCUniProt

Patents 31

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192002Q8NEB9Espacenet
EP 4641201 A22025-10-291573Q8NEB9Espacenet
JP 2025517969 A2025-06-121573Q8NEB9Espacenet
JP 2025517970 A2025-06-122002Q8NEB9Espacenet
JP 2024123008 A2024-09-107622Q8NEB9Espacenet
US 11446398 B22022-09-2062517Q8NEB9Espacenet
JP 2022524081 A2022-04-27165488Q8NEB9Espacenet
US 11078247 B22021-08-038477Q8NEB9Espacenet
US 10918740 B22021-02-169235Q8NEB9Espacenet
US 10869935 B22020-12-229235Q8NEB9Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2720

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant262,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital152,025NIH's project files
R01NS060123Neuronal Autophagy: a Cell-Autonomous Protection Mechanism152,025NIH's project files
P30CA008748Cancer Center Support Grant132,025NIH's project files
R35GM131919The mechanism and regulation of autophagy122,025NIH's project files
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes102,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant92,025NIH's project files
P40OD010440Caenorhabditis Genetics Center92,025NIH's project files
R01CA126792Autophagy and Pro-metastatic Differentiation92,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)82,025NIH's project files

Papers 4970

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42803943PubTator, text miningPubMed
42801082PubTator, text miningPubMed
42711381PubTator, text miningPubMed
42622137PubTator, text miningPubMed
42543371PubTator, text miningPubMed
42503352PubTator, text miningPubMed
42464422PubTator, text miningPubMed
42419369PubTator, text miningPubMed
42368561PubTator, text miningPubMed
42207670PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license