Gene · 5307
PITX1: paired like homeodomain 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PITX1: paired like homeodomain 1. Genes, record 5307. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5307
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P78337 | Pituitary homeobox 1 | 314 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents22
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 56919 | P78337 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 56921 | P78337 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15490 | P78337 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15490 | P78337 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15490 | P78337 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15329 | P78337 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 60955 | P78337 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 60958 | P78337 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 163926 | P78337 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 163929 | P78337 | Espacenet |
1 to 10 of 22
See all 22 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,009
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PITX1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P50HD103525 | WASHINGTON UNIVERSITY INTELLECTUAL AND DEVELOPMENTAL DISABILITIES RESEARCH CENTER | 4 | 2025 |
| T32HG000040 | University of Michigan Training Program in Genomic Science | 4 | 2025 |
| P01HD084387 | Developmental Mechanisms of Human Idiopathic Scoliosis | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 3 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 3 | 2025 |
| U01CA167551 | Colon Cancer Family Registry Cohort | 3 | 2025 |
1 to 10 of 1,009Source NIH's project files
See all 1,009 nih grantsPapers1,358
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Fibroblast proliferative capacity predicts prognosis in idiopathic pulmonary fibrosis and identifies PITX1 as a growth-associated gene. | Sarcoidosis Vasc Diffuse Lung Dis | 2026 | 42813314 | PubTator, text mining | PubMed |
| Coarse-graining analysis for non-invasive, label-free, and quantitative evaluation of undulating motion in cultured oral mucosa epithelial cell sheets. | Regen Ther | 2026 | 42733435 | PubTator, text mining | PubMed |
| PITX1 facilitates the proliferation and tumorigenesis of NSCLC cells via potentiating PHB2-mediated AKT activity. | Cell Signal | 2026 | 42731741 | PubTator, text mining | PubMed |
| Generation of Functional GnRH-Responsive Pituitary-like Organoids from Ovine Embryonic Stem Cells. | Cells | 2026 | 42587770 | PubTator, text mining | PubMed |
| Phase-dependent dynamics of circulating cell-free mitochondrial DNA reflect distinct immunometabolic states. | Rev Inst Med Trop Sao Paulo | 2026 | 42525119 | PubTator, text mining | PubMed |
| LAMA5 links extracellular matrix organization to a candidate WNT-associated endothelial signaling niche during human chondrogenesis. | iScience | 2026 | 42472097 | PubTator, text mining | PubMed |
| Prenatal Diagnosis of PITX1-Related Limb Malformations in the Second Trimester. | Prenat Diagn | 2026 | 42333653 | PubTator, text mining | PubMed |
| Isoliquiritigenin Impedes Breast Cancer Progression through PITX1-PFKP-Mediated Glycolysis Reprogramming. | Oncol Res | 2026 | 42065039 | PubTator, text mining | PubMed |
| Cell-free mitochondrial DNA and microRNA-137 for early diagnosis of preeclampsia. | Front Cardiovasc Med | 2026 | 41993856 | PubTator, text mining | PubMed |
| Mitochondrial signals in the bloodstream: Peripheral signature of mitochondrial dysfunction in mental health. A systematic review. | Neurosci Biobehav Rev | 2026 | 41921723 | PubTator, text mining | PubMed |
1 to 10 of 1,358
See all 1,358 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5307
GET https://conductscience.org/api/genes/v1/5307/patents?page=2