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PKD1: polycystin 1, transient receptor potential channel interacting

1 protein, 25 patents, 0 drugs, 0 trials, 2,649 NIH grants and 5,196 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPKD1HGNC
Namepolycystin 1, transient receptor potential channel interactingHGNC
NCBI Gene ID5310NCBI Gene
HGNC IDHGNC:9008HGNC
EnsemblENSG00000008710NCBI Gene
AliasesPBP, PC1, Pc-1, TRPP1, eliosinNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P98161Polycystin-14,30313Ensembl, GeneID, HGNCUniProt

Patents 25

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1458397P98161Espacenet
EP 4650780 A22025-11-192050P98161Espacenet
EP 4640849 A22025-10-29245P98161Espacenet
EP 4641201 A22025-10-291613P98161Espacenet
JP 2025529142 A2025-09-043496P98161Espacenet
US 12371689 B22025-07-293496P98161Espacenet
JP 2025519096 A2025-06-24245P98161Espacenet
JP 2025517969 A2025-06-121613P98161Espacenet
JP 2025517970 A2025-06-122050P98161Espacenet
WO 2025097000 A12025-05-0834P98161Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2649

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01DK058816ADPKD: Disease Spectrum & Genotype-Phenotype Correlations662,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award212,025NIH's project files
ZIADK075042The role of PKD proteins in regulating tubular morphology212,025NIH's project files
U54DK126126Kansas PKD Research and Translation Core Center192,025NIH's project files
P30DK084567Mayo Center for Cell Signaling in Gastroenterology172,025NIH's project files
R01DK059597Investigation of common disease mechanisms in nonsyndromic and syndromic PKD142,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase132,025NIH's project files
P30DK034989Yale Liver Center132,025NIH's project files
U54DK126114Maryland Polycystic Kidney Disease Research Core Center (MPKD-RCC)122,025NIH's project files
P20GM130423The Kansas Institute for Precision Medicine102,025NIH's project files

Papers 5196

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42796377PubTator, text miningPubMed
42779593PubTator, text miningPubMed
42779582PubTator, text miningPubMed
42770306PubTator, text miningPubMed
42767677PubTator, text miningPubMed
42751568PubTator, text miningPubMed
42744122PubTator, text miningPubMed
42741939PubTator, text miningPubMed
42739200PubTator, text miningPubMed
42702893PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license