Gene · 5320
PLA2G2A: phospholipase A2 group IIA
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PLA2G2A: phospholipase A2 group IIA. Genes, record 5320. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5320
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P14555 | Phospholipase A2, membrane associated | 144 | 17 | Ensembl, GeneID, HGNC |
Source UniProt
Patents104
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4774000 A1 | 2026-07-15 | 1 | P14555 | Espacenet |
| JP 2026026192 A | 2026-02-16 | 26 | P14555 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9577 | P14555 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10465 | P14555 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10466 | P14555 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7363 | P14555 | Espacenet |
| WO 2025169993 A | 2025-08-14 | 6 | P14555 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7363 | P14555 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9577 | P14555 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 10465 | P14555 | Espacenet |
1 to 10 of 104
See all 104 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials5
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT04969991 | VARESPLADIB | PHASE2 | 2025-05-15 | ClinicalTrials.gov |
| NCT01130246 | VARESPLADIB METHYL | PHASE3 | ClinicalTrials.gov | |
| NCT00743925 | VARESPLADIB METHYL | PHASE2 | ClinicalTrials.gov | |
| NCT00525954 | VARESPLADIB METHYL | PHASE2 | ClinicalTrials.gov | |
| NCT00455546 | VARESPLADIB METHYL | PHASE2 | ClinicalTrials.gov |
NIH grants1,438
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PLA2G2A papers | Newest fiscal year |
|---|---|---|---|
| R35GM139641 | Action of Lipolytic Enzymes | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| K24AI130263 | Immunopathology of Indirect Airway Hyperresponsiveness in Asthma | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 3 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 3 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 3 | 2025 |
| P40OD010960 | Viper Resource Grant at Texas A&M University-Kingsville | 3 | 2025 |
| R01DK039773 | Mechanisms of Ischemic Kidney Injury and Repair | 3 | 2025 |
1 to 10 of 1,438Source NIH's project files
See all 1,438 nih grantsPapers3,288
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Identification of Domain Formation During sPLA2 Activity by Biophotonics. | Methods Mol Biol | 2027 | 42778863 | PubTator, text mining | PubMed |
| Clusterin expression and germinal center morphometry help distinguish idiopathic multicentric castleman disease from select lymphadenopathies. | Front Immunol | 2026 | 42824315 | PubTator, text mining | PubMed |
| A systemic neuroendocrine immune axis in breast cancer revealed by MMD regularized cross tissue latent alignment across four independent cohorts. | Comput Biol Med | 2026 | 42762681 | PubTator, text mining | PubMed |
| Camphorquinone-induced phospholipase A2 and cyclooxygenase -2 expression and its roles in 8-isoprostane and prostaglandin E2 production of human dental pulp cells. | J Dent Sci | 2026 | 42688640 | PubTator, text mining | PubMed |
| Varespladib for snakebite envenoming: insights from therapeutic development and clinical trials. | Expert Opin Investig Drugs | 2026 | 42685248 | PubTator, text mining | PubMed |
| Preoperative Serum Alkaline Phosphatase Predicts Arteriovenous Fistula Maturation Failure. | Kidney Int Rep | 2026 | 42569269 | PubTator, text mining | PubMed |
| The Sind krait (Bungarus sindanus): Insights into natural history, venom toxicology, neurotoxic mechanisms, and future directions. | Chem Biol Interact | 2026 | 42562291 | PubTator, text mining | PubMed |
| Ramulus Mori alkaloids (SZ-A) sensitize triple-negative breast cancer to cisplatin via PLA2G2A-mediated ceramide metabolism. | Chin J Nat Med | 2026 | 42476660 | PubTator, text mining | PubMed |
| Comparison of the efficacy of varespladib and coral snake antivenom against the activities of the Amazon coral snake (Micrurus spixii) venom. | Toxicon | 2026 | 42419684 | PubTator, text mining | PubMed |
| Mutation detection in women diagnosed with endometrial cancer: a next-generation sequencing analysis. | Mol Cell Oncol | 2026 | 42376597 | PubTator, text mining | PubMed |
1 to 10 of 3,288
See all 3,288 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5320
GET https://conductscience.org/api/genes/v1/5320/patents?page=2