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PLA2G4A: phospholipase A2 group IVA

1 protein, 23 patents, 1 drug, 1 trial, 2,652 NIH grants and 5,174 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPLA2G4AHGNC
Namephospholipase A2 group IVAHGNC
NCBI Gene ID5321NCBI Gene
HGNC IDHGNC:9035HGNC
EnsemblENSG00000116711NCBI Gene
AliasesGURDP, PLA2G4, cPLA2, cPLA2-alphaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P47712Cytosolic phospholipase A27493Ensembl, GeneID, HGNCUniProt

Patents 23

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-198237P47712Espacenet
EP 4641201 A22025-10-298408P47712Espacenet
JP 2025517969 A2025-06-128408P47712Espacenet
JP 2025517970 A2025-06-128237P47712Espacenet
JP 2025032204 A2025-03-1133543P47712Espacenet
EP 4484957 A12025-01-01124P47712Espacenet
EP 4461818 A22024-11-1333543P47712Espacenet
JP 2024123008 A2024-09-107649P47712Espacenet
WO 2023162878 A2023-08-31124P47712Espacenet
JP 2023058610 A2023-04-2533543P47712Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
GIRIPLADIBCHEMBL2104969Cytosolic phospholipase A2 inhibitorINHIBITORChEMBL

Trials 1

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT00396955GIRIPLADIBPHASE2ClinicalTrials.gov

NIH grants 2652

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant132,025NIH's project files
P30CA016672Cancer Center Support Grant102,025NIH's project files
R01DK039773Mechanisms of Ischemic Kidney Injury and Repair102,025NIH's project files
R35GM139641Action of Lipolytic Enzymes102,025NIH's project files
R01HL019134Angiotensins, Prostaglandins and Adrenergic Interactions82,025NIH's project files
P30DK056341Washington University Nutrition Obesity Research Center72,025NIH's project files
R01DK072381Kidney Injury Molecule-1 in Epithelial Repair62,025NIH's project files
P01CA097132Sphingolipids in Cancer Biology and Therapy52,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant52,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant52,025NIH's project files

Papers 5174

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42801615PubTator, text miningPubMed
42756821PubTator, text miningPubMed
42731694PubTator, text miningPubMed
42715607PubTator, text miningPubMed
42696452PubTator, text miningPubMed
42695246PubTator, text miningPubMed
42688640PubTator, text miningPubMed
42664822PubTator, text miningPubMed
42651958PubTator, text miningPubMed
42476006PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license