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Gene · 53353

LRP1B: LDL receptor related protein 1B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LRP1B: LDL receptor related protein 1B. Genes, record 53353. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/53353

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Gene

Symbol
LRP1B
HGNC
Name
LDL receptor related protein 1B
HGNC
NCBI Gene ID
53353
NCBI Gene
HGNC ID
HGNC:6693
HGNC
Ensembl
ENSG00000168702
NCBI Gene
Aliases
LRP-1B, LRP-DIT, LRPDIT
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NZR2Low-density lipoprotein receptor-related protein 1B4,5990Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910685Q9NZR2Espacenet
EP 4641201 A22025-10-2911091Q9NZR2Espacenet
JP 2025147176 A2025-10-068012Q9NZR2Espacenet
JP 2025529142 A2025-09-042436Q9NZR2Espacenet
JP 2025529142 A2025-09-046923Q9NZR2Espacenet
US 12371689 B22025-07-292436Q9NZR2Espacenet
US 12371689 B22025-07-296923Q9NZR2Espacenet
JP 2025517969 A2025-06-1211091Q9NZR2Espacenet
JP 2025517970 A2025-06-1210685Q9NZR2Espacenet
JP 2025032204 A2025-03-1130981Q9NZR2Espacenet

1 to 10 of 37

See all 37 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,346

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLRP1B papersNewest fiscal year
P30CA016672Cancer Center Support Grant242025
P30CA008748Cancer Center Support Grant182025
U10CA180888SWOG Network Group Operations Center of the NCTN82025
UL1TR001863Yale Clinical and Translational Science Award82025
U10CA180819SWOG Statistics & Data Management Center complex - extension supplement for GY0672025
U10CA180821Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension72025
P30CA033572Cancer Center Support Grant62025
U10CA180820ECOG-ACRIN Network Group Operations Center62025
U10CA180868NRG Oncology Network Group Operations Center62025
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025

1 to 10 of 1,346Source NIH's project files

See all 1,346 nih grants

Papers2,235

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Primary Large B-Cell Lymphomas of Immune-Privileged Sites With IRF4 Rearrangement: Clinicopathological and Molecular Characterization.Mod Pathol202642754234PubTator, text miningPubMed
Molecular differences between poorly and well/moderately differentiated lung adenocarcinoma and their clinical implications.J Thorac Dis202642724192PubTator, text miningPubMed
Unveiling novel transcriptomic prognostic biomarkers for specific breast cancer subtypes and treatment regimens.Pharmacol Rep202642714781PubTator, text miningPubMed
Genomic Landscape of Early-Onset Colorectal Cancer: A Comparative Analysis With Average-Onset Metastatic Colorectal Cancer in a Real-World NGS Cohort.JCO Precis Oncol202642647761PubTator, text miningPubMed
Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.Blood Adv202642616615PubTator, text miningPubMed
Alzheimer's Disease DNA Methylation Index (AD-DMI) and its Association with Late-Life Cognitive Function.NPJ Dement202642583477PubTator, text miningPubMed
Integrated Genomic, Transcriptomic, and Circulating Biomarkers Predict Benefit to Immune Checkpoint Inhibitor Plus Chemotherapy in Advanced Non-Small Cell Lung Cancer.MedComm (2020)202642415854PubTator, text miningPubMed
Pan-cancer analysis of tissue-plasma genomic concordance reveals enhanced concordance with liver metastasis and plasma clonality as predictor of poorer overall survival.NPJ Precis Oncol202642399342PubTator, text miningPubMed
Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer.Cancer Med202642286843PubTator, text miningPubMed
Integrated environmental and genomic analysis reveals the drivers and genetic mechanisms of agro-climatic adaptation in geese.BMC Genomics202642218382PubTator, text miningPubMed

1 to 10 of 2,235

See all 2,235 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/53353

GET https://conductscience.org/api/genes/v1/53353/patents?page=2