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Gene · 53369

HDL3: Huntington-like neurodegenerative disorder 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HDL3: Huntington-like neurodegenerative disorder 2. Genes, record 53369. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/53369

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Gene

Symbol
HDL3
Name
Huntington-like neurodegenerative disorder 2
NCBI Gene ID
53369
Aliases
HLN2
Type
unknown

Source NCBI Gene

Proteins0

Reviewed human proteins whose Swiss-Prot entry states the gene.

None in this release.

Patents0

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

None in this release.

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants764

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHDL3 papersNewest fiscal year
P30DK017047Diabetes Research Center222025
P30DK035816Nutrition Obesity Research Center132025
P01HL116263HDL Function in Human Disease92025
P01HL128203Multi-disciplinary Approaches to HDL Structure, Assembly, and Functional Heterogeneity52025
T32HL007024Cardiovascular Epidemiology Institutional Training52025
P30DK019525University of Pennsylvania Diabetes Research Center42025
P30DK056341Washington University Nutrition Obesity Research Center42025
I01BX000900Effect of SMSr on VLDL metabolism and atherosclerosis32025
P20GM103499South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE)32025
P30CA138313Medical University of South Carolina - Cancer Center Support Grant32025

1 to 10 of 764Source NIH's project files

See all 764 nih grants

Papers1,954

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Effects of Protocatechuic Acid on Endothelial Function and HDL Functionality in Hypercholesterolemic Subjects: A Randomized Double-Blind Placebo-Controlled Trial.Nutrients202642797039PubTator, text miningPubMed
Association of HDL2b with chronic kidney disease in type 2 diabetes mellitus populations.Front Endocrinol (Lausanne)202642638941PubTator, text miningPubMed
Impact of altered HDL2b/HDL3 ratio on the function of innate immune cells in sepsis.Lipids Health Dis202642374480PubTator, text miningPubMed
Lipid and High-Density Lipoprotein (HDL) Subfraction Changes in Premenopausal and Postmenopausal Women With Breast Cancer Receiving Hormonal Therapy.Cureus202642292016PubTator, text miningPubMed
Dissociation Between Cholesteryl Ester Transfer Protein Mass and Activity in Coronary Artery Disease Patients with Elevated High-Density Lipoprotein Cholesterol: Implications for High-Density Lipoprotein Function and Residual Cardiovascular Risk.
Anatol J Cardiol202642037376PubTator, text miningPubMed
Deciphering high density lipoprotein (HDL) structure-function: Detailed analysis of HDL subfractions reveals molecular differences leading to atherosclerosis risk.Int J Biol Macromol202641991129PubTator, text miningPubMed
A narrative review of impacts of apolipoproteins on atherosclerotic coronary plaques.NPJ Cardiovasc Health202641775966PubTator, text miningPubMed
Effects of Phenolic Acids-Rich Brussels Chicory on Fasting and Postprandial Vascular Function, HDL Functions, and Subclass Profiles in Healthy Overweight Men: A Randomized, Controlled, Single-Blind, Three-Way Crossover Study.
Mol Nutr Food Res202641761871PubTator, text miningPubMed
Heart failure etiology and lipoprotein subfractions: Insight from the SMARTEX-HF study.Int J Cardiol Heart Vasc202641736908PubTator, text miningPubMed
Pathogenesis and intervention strategies for metabolic dysfunction-associated fatty liver disease from the perspective of the gut-microbiota-liver axis.Front Immunol202641716420PubTator, text miningPubMed

1 to 10 of 1,954

See all 1,954 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/53369

GET https://conductscience.org/api/genes/v1/53369/grants?page=2