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Gene · 5346

PLIN1: perilipin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PLIN1: perilipin 1. Genes, record 5346. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5346

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Gene

Symbol
PLIN1
HGNC
Name
perilipin 1
HGNC
NCBI Gene ID
5346
NCBI Gene
HGNC ID
HGNC:9076
HGNC
Ensembl
ENSG00000166819
NCBI Gene
Aliases
FPLD4, PERI, PLIN
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60240Perilipin-15220Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457347O60240Espacenet
JP 2026004568 A2026-01-1457348O60240Espacenet
EP 4650780 A22025-11-193978O60240Espacenet
JP 2025529142 A2025-09-043518O60240Espacenet
US 12371689 B22025-07-293518O60240Espacenet
JP 2025517970 A2025-06-123978O60240Espacenet
JP 2025004061 A2025-01-147O60240Espacenet
US 11446398 B22022-09-2061932O60240Espacenet
US 11446398 B22022-09-2061933O60240Espacenet
US 11400116 B22022-08-021853O60240Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,936

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePLIN1 papersNewest fiscal year
P30DK020572Michigan Diabetes Research Center (MDRC)202025
P30DK056341Washington University Nutrition Obesity Research Center132025
R01DK062292Analysis of Cellular Plasticity in White Adipose Tissue.122025
R01DK076629Analysis of Lipolytic Trafficking in Adipocytes.122025
R01DK105448Genetic and Metabolic Basis of Familial Lipodystrophies102025
P30DK019525University of Pennsylvania Diabetes Research Center92025
P30DK089503Michigan Nutrition Obesity Research Center82025
P30CA016672Cancer Center Support Grant72025
P30DK072476Pennington/Louisiana NORC72025
ZIADK047050Molecular and Clinical Studies of Insulin Resistance72025

1 to 10 of 1,936Source NIH's project files

See all 1,936 nih grants

Papers3,486

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Altered Lipolytic Protein Expression in Tumor-Associated Adipose Tissue Correlates with Aggressive Breast Cancer Features.Cancers (Basel)202642794967PubTator, text miningPubMed
Lipid droplet-mitochondria contact sites as druggable spatial-pharmacology targets in respiratory disease: cross-cell-type mechanisms and translational strategies.Front Cell Dev Biol202642769092PubTator, text miningPubMed
A nucleus-associated miR-661-C/EBPα-PPARγ regulatory axis skews BMSC lineage commitment in SONFH.Exp Cell Res202642759595PubTator, text miningPubMed
Advanced glycation end products drive blood-brain barrier lipid dysregulation via RAGE-ABCA1 signaling to promote neurovascular dysfunction in Alzheimer's disease.Mol Psychiatry202642686999PubTator, text miningPubMed
Unraveling the toxicological mechanisms of PFAS in metabolic diseases by network toxicology and molecular docking.Environ Pollut202642641853PubTator, text miningPubMed
[miR-454-3p suppresses the proliferation of abdominal preadipocytes in broilers].Sheng Wu Gong Cheng Xue Bao202642638056PubTator, text miningPubMed
Targeting AHNAK ameliorates osteonecrosis of the femoral head and affects adipogenic pathways involving Smad/PPARγ.Bone Joint Res202642613017PubTator, text miningPubMed
Fractionated proteomics identifies a protein network mitigating resistance exercise-induced damage in human skeletal muscle.Nat Commun202642521682PubTator, text miningPubMed
Psoriasis-Obesity-Related Gene COX7C Promotes Keratinocyte Proliferation and Positively Regulates Inflammatory Responses in Psoriasis.J Cell Mol Med202642487278PubTator, text miningPubMed
LD-associated signatures identified by perilipin-based proximity labeling proteomics reveal GNA14 as a therapeutic and prognostic target in renal cell carcinoma.Cancer Gene Ther202642432218PubTator, text miningPubMed

1 to 10 of 3,486

See all 3,486 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5346

GET https://conductscience.org/api/genes/v1/5346/patents?page=2