Gene · 5351
PLOD1: procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PLOD1: procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. Genes, record 5351. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5351
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q02809 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | 727 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 59072 | Q02809 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 188 | Q02809 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 10522 | Q02809 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7381 | Q02809 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7381 | Q02809 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 188 | Q02809 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 10522 | Q02809 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 10522 | Q02809 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 10529 | Q02809 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 66648 | Q02809 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants884
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PLOD1 papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD000256 | Collagen-related diseases | 4 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P01AI063302 | The intersection of innate and adaptive immunity to intracellular pathogens | 2 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 2 | 2025 |
| P20GM103436 | IDeA Networks of Biomedical Research Excellence in Kentucky | 2 | 2025 |
| P20GM121327 | University of Kentucky Center for Cancer Metabolism | 2 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 2 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 884Source NIH's project files
See all 884 nih grantsPapers1,607
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7-dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma. | Adv Sci (Weinh) | 2026 | 42801660 | PubTator, text mining | PubMed |
| Recombinant Production and Characterization of Human Enzymes Responsible for Collagen Lysine Post-translational Modifications. | Methods Mol Biol | 2026 | 42681151 | PubTator, text mining | PubMed |
| Between myopathy and mortality: Challenges in the diagnosis of PLOD1-related kyphoscoliotic Ehlers-Danlos syndrome. | J Neuromuscul Dis | 2026 | 42667135 | PubTator, text mining | PubMed |
| Metabolic-epigenetic reprogramming via the PLOD1-PFKP axis drives cisplatin resistance in HNSCC. | Acta Pharm Sin B | 2026 | 42592154 | PubTator, text mining | PubMed |
| Lactate-induced H3K4me3 histone mark promotes PLOD1-driven prostate cancer invasion. | Cell Death Dis | 2026 | 42414254 | PubTator, text mining | PubMed |
| PLOD1 Drives Head and Neck Squamous Cell Carcinoma Progression Through P4HA2-Mediated Activation of the FAK/PI3K/AKT/mTOR Axis. | J Cell Mol Med | 2026 | 42400233 | PubTator, text mining | PubMed |
| From Stress to Survival: Trophoblast-Derived Extracellular Vesicle Proteome Captures Aspirin-Driven Cellular Reprogramming in a Preeclampsia Model. | Pharmaceutics | 2026 | 42357292 | PubTator, text mining | PubMed |
| Structural and mechanistic insights into the catalytic versatility of lysyl hydroxylases in collagen post-translational modifications. | J Biol Chem | 2026 | 42314906 | PubTator, text mining | PubMed |
| Kyphoscoliotic Ehlers-Danlos syndrome due to a novel homozygous PLOD1 variant: severe vascular involvement and molecular diagnosis. | BMC Med Genomics | 2026 | 42277864 | PubTator, text mining | PubMed |
| Proteomic profiling of olfactory exfoliates from people with subjective cognitive complaints reveal networks of olfactory biomarkers of cognitive performance. | Front Aging Neurosci | 2026 | 42253369 | PubTator, text mining | PubMed |
1 to 10 of 1,607
See all 1,607 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5351
GET https://conductscience.org/api/genes/v1/5351/patents?page=2