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PLP1: proteolipid protein 1

1 protein, 159 patents, 0 drugs, 0 trials, 3,505 NIH grants and 5,508 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolPLP1HGNC
Nameproteolipid protein 1HGNC
NCBI Gene ID5354NCBI Gene
HGNC IDHGNC:9086HGNC
EnsemblENSG00000123560NCBI Gene
AliasesGPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P60201Myelin proteolipid protein2771Ensembl, GeneID, HGNCUniProt

Patents 159

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4824265 A12026-10-215P60201Espacenet
EP 4824265 A12026-10-216P60201Espacenet
US 12642851 B22026-06-02211P60201Espacenet
JP 2026504767 A2026-02-10211P60201Espacenet
JP 2026004568 A2026-01-1460237P60201Espacenet
JP 2026004568 A2026-01-1460239P60201Espacenet
EP 4670794 A22025-12-3111P60201Espacenet
US 12502436 B22025-12-234977P60201Espacenet
JP 2025181835 A2025-12-114977P60201Espacenet
JP 2025539844 A2025-12-097P60201Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3505

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIANS003119Multimodal MRI in Multiple Sclerosis112,025NIH's project files
P01AI039671Costimulatory Mechanisms of Autoimmunity102,025NIH's project files
P30CA008748Cancer Center Support Grant92,025NIH's project files
R28AA012725Brain Tissue Resource Center for Alcohol Research72,025NIH's project files
P30CA016087Cancer Center Support Grant62,025NIH's project files
P30CA043703Case Comprehensive Cancer Center Support Grant62,025NIH's project files
P51OD011092Support for National Primate Research Center62,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award62,025NIH's project files
P30CA016672Cancer Center Support Grant52,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital52,025NIH's project files

Papers 5508

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42809393PubTator, text miningPubMed
42809343PubTator, text miningPubMed
42778423PubTator, text miningPubMed
42777860PubTator, text miningPubMed
42700057PubTator, text miningPubMed
42636412PubTator, text miningPubMed
42587728PubTator, text miningPubMed
42490029PubTator, text miningPubMed
42465930PubTator, text miningPubMed
42397408PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license