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Gene · 5355

PLP2: proteolipid protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PLP2: proteolipid protein 2. Genes, record 5355. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5355

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Gene

Symbol
PLP2
HGNC
Name
proteolipid protein 2
HGNC
NCBI Gene ID
5355
NCBI Gene
HGNC ID
HGNC:9087
HGNC
Ensembl
ENSG00000102007
NCBI Gene
Aliases
A4, A4-LSB, A4LSB, MGC126187
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q04941Proteolipid protein 21520Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1460248Q04941Espacenet
EP 4650780 A22025-11-199760Q04941Espacenet
JP 2025529142 A2025-09-043523Q04941Espacenet
US 12371689 B22025-07-293523Q04941Espacenet
JP 2025517970 A2025-06-129760Q04941Espacenet
US 11446398 B22022-09-2069586Q04941Espacenet
US 11400116 B22022-08-022704Q04941Espacenet
JP 2022524081 A2022-04-27172557Q04941Espacenet
US 11078247 B22021-08-038627Q04941Espacenet
US 11047010 B22021-06-293222Q04941Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,112

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePLP2 papersNewest fiscal year
P30CA068485Cancer Center Support Grant52025
P30DA018343Yale/NIDA Neuroproteomics Center52025
R01MH077681Cholinergic Contribution to Circuits Guiding Behavioral Responses to Stressors52025
P30CA016087Cancer Center Support Grant42025
R01AR077578Mechanisms of Cu-binding factors to promote myogenic gene expression42025
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P01CA019014Viral Oncogenesis, Latency, and Replication22025
P30CA010815Consolidated Basic Cancer Research Program22025
P30CA023168Cancer Center Support Grant22025

1 to 10 of 1,112Source NIH's project files

See all 1,112 nih grants

Papers1,588

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Ten-Gene Transcriptomic Biomarker Panel for Glioma Classification and Prognosis Identified via Integrative Hypergraph and Rough Set Analysis.Cancers (Basel)202642192936PubTator, text miningPubMed
Reduced YTHDF2 inhibits PD-L1 expression by stabilizing m6A-containing SPOP mRNA in colorectal cancer.Cell Death Dis202641872151PubTator, text miningPubMed
Selective Toxicity of Nicotinic Insecticides: Responsibility of Varied Amino Acid(s) in the Ligand-Docking Pocket between Insect versus Mammalian Nicotinic Acetylcholine Receptors.Chem Res Toxicol202641785389PubTator, text miningPubMed
Targeting tRNA-Arg-TCT-4-1 suppresses cancer cell growth and tumorigenesis.bioRxiv202641757043PubTator, text miningPubMed
Employing a Combination of Chemoattractants to Trap Glioblastoma Cells in a Macroporous Hydrogel.Pharmaceutics202641754971PubTator, text miningPubMed
Characterization of the Hydrogel-Binding Mechanism of Phellinus linteus Polysaccharides and Polymerized Whey Protein by SR-IR Technology and Its Application in Goat Milk Yogurt.Foods202641750890PubTator, text miningPubMed
Role of autophagy in antiviral innate immunity.Cell Mol Biol Lett202641735833PubTator, text miningPubMed
Epigenetically-controlled CEBPB regulates kidney cancer tumorigenesis via GPD1L-mediated ether lipid synthesis.Cell Death Dis202641565622PubTator, text miningPubMed
Multiple sources of β2*-nicotinic acetylcholine receptor binding are differentially affected during tobacco smoking abstinence as revealed by Independent Component Analysis of [18F]Flubatine PET images.
Neuropsychopharmacology202641559453PubTator, text miningPubMed
Discovery of a [4Fe-4S] cluster in the PRRSV Nsp1α leader protease reveals host-virus interplay in its downstream functions.bioRxiv202641542491PubTator, text miningPubMed

1 to 10 of 1,588

See all 1,588 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5355

GET https://conductscience.org/api/genes/v1/5355/patents?page=2