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Gene · 537

ATP6AP1: ATPase H+ transporting accessory protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATP6AP1: ATPase H+ transporting accessory protein 1. Genes, record 537. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/537

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Gene

Symbol
ATP6AP1
HGNC
Name
ATPase H+ transporting accessory protein 1
HGNC
NCBI Gene ID
537
NCBI Gene
HGNC ID
HGNC:868
HGNC
Ensembl
ENSG00000071553
NCBI Gene
Aliases
16A, ATP6IP1, ATP6S1, Ac45, CF2, ORF, VATPS1, XAP-3, XAP3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15904V-type proton ATPase subunit S14709Ensembl, GeneID, HGNC

Source UniProt

Patents52

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026079407 A2026-04-16105Q15904Espacenet
US 12540940 B22026-02-0313Q15904Espacenet
JP 2025147176 A2025-10-061241Q15904Espacenet
JP 2025529142 A2025-09-04522Q15904Espacenet
JP 2025529142 A2025-09-045547Q15904Espacenet
US 12371689 B22025-07-29522Q15904Espacenet
US 12371689 B22025-07-295547Q15904Espacenet
JP 2025062604 A2025-04-147492Q15904Espacenet
EP 4516316 A12025-03-05105Q15904Espacenet
JP 2025028160 A2025-02-281241Q15904Espacenet

1 to 10 of 52

See all 52 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,040

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATP6AP1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant92025
P30CA016672Cancer Center Support Grant92025
P30CA023168Cancer Center Support Grant42025
P30ES025128Center for Human Health and the Environment (CHHE)42025
P42ES027704Comprehensive tools and models for addressing exposure to mixtures during environmental emergency-related contamination events42025
P30CA022453CANCER CENTER SUPPORT GRANT32025
R01DK099551New Congenital Disorders of Glycosylation: Therapy and Models32025
R01HL072304Role of ABCG1, ABCG5 and ABCG8 in Sterol Metabolism32025
R35GM131919The mechanism and regulation of autophagy32025
T32AI060537Integrative Microbiology Program32025

1 to 10 of 1,040Source NIH's project files

See all 1,040 nih grants

Papers1,446

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Niclosamide suppresses breast cancer progression and enhances paclitaxel sensitivity by targeting the ATP6AP1-YY1-XIAP axis.Acta Pharmacol Sin202642773187PubTator, text miningPubMed
Cholesteric fingers from a magnetic perspective: Topology, energetics, and interactions.Phys Rev E202642629780PubTator, text miningPubMed
Construction of CF2 moieties in FDA-approved drugs (2016-2025): industrial routes, mechanisms, and scale-up considerations.Beilstein J Org Chem202642577633PubTator, text miningPubMed
Expression patterns of pyroptosis-related genes in atrial fibrillation and their application in diagnostic models.Medicine (Baltimore)202642499091PubTator, text miningPubMed
Visible-Light-Induced Radical Cascade Cyclization of 1,7-Enynes to Access CF2-Containing Indenoquinolines by an Electron Donor.J Org Chem202642461079PubTator, text miningPubMed
Greater Japanese horseshoe bats (Rhinolophus nippon) gradually converge their echolocation call frequency to colony members.J Comp Physiol A Neuroethol Sens Neural Behav Physiol202642337114PubTator, text miningPubMed
Granular Cell Dermatofibroma Demonstrates Loss-of-Function Mutations in V-ATPase Component Genes.J Cutan Pathol202642108978PubTator, text miningPubMed
[ATPase H+ transporter expression with prognosis in hepatocellular carcinoma].Zhonghua Gan Zang Bing Za Zhi202642036227PubTator, text miningPubMed
Decoding Fibroblast Diversity Associated with the Postnatal Loss of Cardiac Regenerative Capacity.Int J Mol Sci202641898567PubTator, text miningPubMed
Spectrum and functions of ion channels and transporters in osteoclasts.Bone Res202641896521PubTator, text miningPubMed

1 to 10 of 1,446

See all 1,446 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/537

GET https://conductscience.org/api/genes/v1/537/patents?page=2