Gene · 53905
DUOX1: dual oxidase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DUOX1: dual oxidase 1. Genes, record 53905. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/53905
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9NRD9 | Dual oxidase 1 | 1,551 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents63
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 44301 | Q9NRD9 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 44302 | Q9NRD9 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 44303 | Q9NRD9 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5149 | Q9NRD9 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4746 | Q9NRD9 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4470 | Q9NRD9 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 4471 | Q9NRD9 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1335 | Q9NRD9 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6214 | Q9NRD9 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1335 | Q9NRD9 | Espacenet |
1 to 10 of 63
See all 63 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,077
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DUOX1 papers | Newest fiscal year |
|---|---|---|---|
| ZIABC010677 | NADPH Oxidases as Novel Targets for Cancer Therapy | 11 | 2025 |
| P30ES005605 | Environmental Health Sciences Research Center | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| R01DK015070 | Thyroid Physiology Studies of Inherited Disorders | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30DK054759 | Precision Medicine Center for Cystic Fibrosis | 4 | 2025 |
| P50AA011999 | Southern California Research Center for ALPD and Cirrhosis | 4 | 2025 |
| P30DK020595 | Diabetes Research and Training Center | 3 | 2025 |
| P51OD011104 | Tulane National Primate Research Center | 3 | 2025 |
| P20GM103449 | Vermont Biomedical Research Network-Vermont INBRE | 2 | 2025 |
1 to 10 of 1,077Source NIH's project files
See all 1,077 nih grantsPapers1,614
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Thyroid hormone synthesis and AITD-related inflammatory factors are modulated during early pregnancy in ewes. | Theriogenology | 2027 | 42790002 | PubTator, text mining | PubMed |
| "NADPH Oxidases: Central Regulators of Redox Signalling and Cellular Homeostasis". | Curr Diabetes Rev | 2026 | 42695285 | PubTator, text mining | PubMed |
| Disulfidptosis- and Ferroptosis-Related Gene Signatures in Rheumatoid Arthritis: Association Analysis and Diagnostic Model Construction. | Kaohsiung J Med Sci | 2026 | 42690169 | PubTator, text mining | PubMed |
| A hybrid machine learning framework with two-step feature selection for identifying key biomarkers and drug targets in monkeypox. | Biochem Biophys Rep | 2026 | 42434339 | PubTator, text mining | PubMed |
| Human-relevant exposure to mixtures of rare earth elements disrupts T3 homeostasis through impaired synthesis and conversion in human Thyrocytes. | Toxicol Appl Pharmacol | 2026 | 42364782 | PubTator, text mining | PubMed |
| From Defense to Disease: NADPH Oxidase in Cellular Function and Dysregulation. | J Immunol Res | 2026 | 42360039 | PubTator, text mining | PubMed |
| Structural bioinformatic studies of eight integral transmembrane NADPH oxidases and their AlphaFold 3 predicted QTY analogs with reduced hydrophobicity. | PLoS One | 2026 | 42268815 | PubTator, text mining | PubMed |
| S100A8-associated inflammatory microenvironment is related to its cell-of-origin and potentiates BRAF inhibitor resistance in papillary craniopharyngioma. | Clin Exp Med | 2026 | 41920205 | PubTator, text mining | PubMed |
| Corrigendum to: DUOX1 inhibits the progression of rheumatoid arthritis by regulating the NF-κB pathway in vitro. | Allergol Immunopathol (Madr) | 2026 | 41910349 | PubTator, text mining | PubMed |
| Genetic parameter estimation and genome-wide association study of fiber characteristics for cashmere goats in the United States. | J Anim Sci | 2026 | 41830137 | PubTator, text mining | PubMed |
1 to 10 of 1,614
See all 1,614 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/53905
GET https://conductscience.org/api/genes/v1/53905/patents?page=2