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Gene · 53947

A4GALT: alpha 1,4-galactosyltransferase (P1PK blood group)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. A4GALT: alpha 1,4-galactosyltransferase (P1PK blood group). Genes, record 53947. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/53947

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Gene

Symbol
A4GALT
HGNC
Name
alpha 1,4-galactosyltransferase (P1PK blood group)
HGNC
NCBI Gene ID
53947
NCBI Gene
HGNC ID
HGNC:18149
HGNC
Ensembl
ENSG00000128274
NCBI Gene
Aliases
A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NPC4Lactosylceramide 4-alpha-galactosyltransferase3530Ensembl, GeneID, HGNC

Source UniProt

Patents48

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437141Q9NPC4Espacenet
JP 2026004568 A2026-01-1437142Q9NPC4Espacenet
JP 2026004568 A2026-01-1437143Q9NPC4Espacenet
EP 4650780 A22025-11-191264Q9NPC4Espacenet
EP 4641201 A22025-10-29899Q9NPC4Espacenet
JP 2025529142 A2025-09-04169Q9NPC4Espacenet
US 12371689 B22025-07-29169Q9NPC4Espacenet
JP 2025517969 A2025-06-12899Q9NPC4Espacenet
JP 2025517970 A2025-06-121264Q9NPC4Espacenet
WO 2025093745 A12025-05-0841Q9NPC4Espacenet

1 to 10 of 48

See all 48 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,266

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleA4GALT papersNewest fiscal year
ZIADK029046Methods to accelerate protein structure determination by solution NMR122025
P20GM103424Louisiana Biomedical Research Network72025
P30CA016672Cancer Center Support Grant52025
P30DK034854Integrated Epithelial and Muscosal Biology52025
P30CA008748Cancer Center Support Grant42025
P30CA016086Cancer Center Support Grant42025
P30CA016087Cancer Center Support Grant42025
R37DA045657Mechanistic insights into LSD actions at 5-HT2A serotonin receptors42025
ZIABC011055Serum Antibody Profiling with a Carbohydrate Microarray42025
R01DK049419Role of bFGF low affinity receptors in childhood HIVAN32025

1 to 10 of 1,266Source NIH's project files

See all 1,266 nih grants

Papers2,770

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Case Report: Concurrent Fabry disease, IgA nephropathy and undifferentiated connective tissue disease in a female with normal enzyme activity.Front Immunol202642824490PubTator, text miningPubMed
A novel P1PK-null allele in a Belgian patient with a p phenotype.Transfusion202642678021PubTator, text miningPubMed
Central nervous system biomarkers in Fabry disease: Mechanisms, clinical evidence, and translational integration.Mol Genet Metab202642623976PubTator, text miningPubMed
Surface Functionalization of Small Extracellular Vesicles Derived from Caco-2 and HEK293T Cells in the Neutralization of Shiga Toxin 1 Subunit B.Bioconjug Chem202642615512PubTator, text miningPubMed
Unraveling A4GALT Mechanism and Its Modulation With Adamantyl-Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies.Angew Chem Int Ed Engl202642559965PubTator, text miningPubMed
Evaluating the relationship between antidrug antibodies and efficacy and safety outcomes in patients with Fabry disease receiving enzyme replacement therapy: a systematic literature review.Orphanet J Rare Dis202642464344PubTator, text miningPubMed
Functional dissection of HCMV gB's autonomous fusion activity provides insights into how polymorphisms in clinical isolates confer distinct characteristics.mBio202642439560PubTator, text miningPubMed
ECG parameters to detect cardiac involvement in Fabry disease.BMC Cardiovasc Disord202642436424PubTator, text miningPubMed
Pathogenic mechanisms in Fabry disease.Front Med (Lausanne)202642415779PubTator, text miningPubMed
Automated quantification of skin Gb3 load and white matter lesion assessment in Fabry disease.Orphanet J Rare Dis202642415116PubTator, text miningPubMed

1 to 10 of 2,770

See all 2,770 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/53947

GET https://conductscience.org/api/genes/v1/53947/patents?page=2